Hepatitis C infection: A multi-faceted systemic disease with clinical, patient reported and economic consequences  Zobair M. Younossi, Aybike Birerdinc,

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Hepatitis C infection: A multi-faceted systemic disease with clinical, patient reported and economic consequences  Zobair M. Younossi, Aybike Birerdinc, Linda Henry  Journal of Hepatology  Volume 65, Issue 1, Pages S109-S119 (October 2016) DOI: 10.1016/j.jhep.2016.07.005 Copyright © 2016 European Association for the Study of the Liver Terms and Conditions

Fig. 1 How to capture the comprehensive benefits approach for measuring the burden of HCV to patients and to society. HCV, hepatitis C virus; EHM, extra-hepatic manifestations; HQRL, health-related quality of life; WP, window phase; ICER, incremental cost-effectiveness ratio; PRO, patient related outcomes. Journal of Hepatology 2016 65, S109-S119DOI: (10.1016/j.jhep.2016.07.005) Copyright © 2016 European Association for the Study of the Liver Terms and Conditions

Fig. 2 HCV and progression of liver disease. HCV, hepatitis C virus; SVR, sustained virological response; HCC, hepatocellular carcinoma; USA, United States of America. Journal of Hepatology 2016 65, S109-S119DOI: (10.1016/j.jhep.2016.07.005) Copyright © 2016 European Association for the Study of the Liver Terms and Conditions