Advanced acral melanoma

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Presentation transcript:

Advanced acral melanoma Franki Lambert Smith, MD, Joshua Wisell, MD, Mariah Brown, MD JAAD Case Reports Volume 1, Issue 3, Pages 166-168 (May 2015) DOI: 10.1016/j.jdcr.2015.03.010 Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 A to C, Acral melanoma. Clinical presentation of large, fungating, malodorous mass obscuring the left great toe with large areas of necrosis. D, Firm, lobulated mass in left groin. JAAD Case Reports 2015 1, 166-168DOI: (10.1016/j.jdcr.2015.03.010) Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions

Fig 2 Pathology of acral melanoma. A, Histologically the lesion is densely cellular with minimal intervening stroma. B and C, Higher-power magnification demonstrates epithelioid tumor cells with marked cellular and nuclear atypia. D, An immunohistochemical study for S100 strongly and diffusely labels the tumor cells. (Original magnification: ×40.) (A to C, Hematoxylin-eosin stain; original magnifications: A, ×40; B, ×100; C, ×200.) JAAD Case Reports 2015 1, 166-168DOI: (10.1016/j.jdcr.2015.03.010) Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions