Outcomes of Human Leukocyte Antigen–Matched Sibling Donor Hematopoietic Cell Transplantation in Chronic Lymphocytic Leukemia: Myeloablative Versus Reduced-

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Presentation transcript:

Outcomes of Human Leukocyte Antigen–Matched Sibling Donor Hematopoietic Cell Transplantation in Chronic Lymphocytic Leukemia: Myeloablative Versus Reduced- Intensity Conditioning Regimens  Ronald M. Sobecks, Jose F. Leis, Robert Peter Gale, Kwang Woo Ahn, Xiaochun Zhu, Mitchell Sabloff, Marcos de Lima, Jennifer R. Brown, Yoshihiro Inamoto, Gregory A. Hale, Mahmoud D. Aljurf, Rammurti T. Kamble, Jack W. Hsu, Steven Z. Pavletic, Baldeep Wirk, Matthew D. Seftel, Ian D. Lewis, Edwin P. Alyea, Jorge Cortes, Matt E. Kalaycio, Richard T. Maziarz, Wael Saber  Biology of Blood and Marrow Transplantation  Volume 20, Issue 9, Pages 1390-1398 (September 2014) DOI: 10.1016/j.bbmt.2014.05.020 Copyright © 2014 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 Cumulative incidence curves comparing (A) grades II to IV and (B) grades III to IV acute GVHD, (C) chronic GVHD, (D) progression/relapse, and (E) TRM between MA and RIC allogeneic HCT for CLL. Biology of Blood and Marrow Transplantation 2014 20, 1390-1398DOI: (10.1016/j.bbmt.2014.05.020) Copyright © 2014 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 2 Comparison of progression-free survival between MA and RIC allogeneic HCT for CLL. (A) Performed in 2000 or earlier. (B) Performed after 2000. Biology of Blood and Marrow Transplantation 2014 20, 1390-1398DOI: (10.1016/j.bbmt.2014.05.020) Copyright © 2014 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 3 Comparison of overall survival between MA and RIC allogeneic HCT for CLL. (A) Performed in 2000 or earlier. (B) Performed after 2000. Biology of Blood and Marrow Transplantation 2014 20, 1390-1398DOI: (10.1016/j.bbmt.2014.05.020) Copyright © 2014 American Society for Blood and Marrow Transplantation Terms and Conditions