A Kinase Gets Caspases into Shape

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A Kinase Gets Caspases into Shape Denise J. Montell Cell Volume 126, Issue 3, Pages 450-452 (August 2006) DOI: 10.1016/j.cell.2006.07.017 Copyright © 2006 Elsevier Inc. Terms and Conditions

Figure 1 The Regulation and Functions of Caspases The fly protein DIAP1 is a direct inhibitor of both the apical caspase DRONC and the effector caspases that DRONC activates. A frequent consequence of such caspase activation is apoptosis. However, both apical and effector caspases have been implicated in nonapoptotic functions, such as the differentiation of sensory organ precursors (Kuranaga et al., 2006), sperm individualization (Arama et al., 2003), border cell migration (Geisbrecht and Montell, 2004), and the morphology of sensory and tracheal cells (Oshima et al., 2006). Cell 2006 126, 450-452DOI: (10.1016/j.cell.2006.07.017) Copyright © 2006 Elsevier Inc. Terms and Conditions