Human leukocyte antigen expression by peritoneal macrophages from women with pelvic endometriosis is depressed but coordinated with costimulatory molecule.

Slides:

Advertisements

Similar presentations

What’s the delay? A qualitative study of women’s experiences of reaching a diagnosis of endometriosis Karen Ballard, Ph.D., Karen Lowton, Ph.D., Jeremy.

Advertisements

The endometria of patients with endometriosis show higher expression of class I human leukocyte antigen than the endometria of healthy women María del.

Incremental direct and indirect cost burden attributed to endometriosis surgeries in the United States Ahmed M. Soliman, Ph.D., M.S., Hugh Taylor, M.D.,

Ratio between inner cell mass diameter and blastocyst diameter is correlated with successful pregnancy outcomes of single blastocyst transfers Miriam.

Daily physical activity and hot flashes in the Study of Women's Health Across the Nation (SWAN) Flashes Study Carolyn Gibson, M.P.H., M.S., Karen Matthews,

Christine Jablonski, M. D. , Marco Alifano, M. D

Karl R. Hansen, M. D. , Ph. D. , George M. Hodnett, M. D

Outdoor air pollution and sperm quality

The relative effects of hormones and relationship factors on sexual function of women through the natural menopausal transition Lorraine Dennerstein,

Infertility evaluation and treatment among women in the United States

Fernando Zegers-Hochschild, M.D. Fertility and Sterility

Human leukocyte antigen-G, a ligand for the natural killer receptor KIR2DL4, is expressed by eutopic endometrium only in the menstrual phase Masaaki.

Michael M. Alper, M.D. Fertility and Sterility

Ovarian size and blood flow in women with polycystic ovary syndrome and their correlations with endocrine parameters Enrico Carmina, M.D., Francesco.

High soluble CD44 concentration in peritoneal fluid in endometriosis

Why natural killer cells are not enough: a further understanding of killer immunoglobulin- like receptor and human leukocyte antigen Diana Alecsandru,

Brett McKinnon, Ph. D. , Nick A. Bersinger, Ph. D. , Alexander W

Clinical application of oocyte vitrification: a systematic review and meta-analysis of randomized controlled trials Ana Cobo, Ph.D., César Diaz, M.D.

Hysterosalpingography with use of mobile C-arm fluoroscopy

Dennis J. Hand, Ph. D. , Vanessa L. Short, Ph. D. , M. P. H. , Diane J

Hepatitis and reproduction

Relation between anatomical courses of the intramural portions of the uterine tubes and pelvic endometriosis Stanislaw Rozewicki, M.D., Ph.D., Anna Radomska,

Can an educational DVD improve the acceptability of elective single embryo transfer? A randomized controlled study Nicole Hope, M.B., B.S., Hon., Luk.

Risk of depression and other mental health disorders in women with polycystic ovary syndrome: a longitudinal study Angela Kerchner, B.A., Whitney Lester,

Sanghoon Lee, M. D. , Elke Heytens, Ph. D. , Fred Moy, Ph. D

Temporal trends in clomiphene citrate use: a population-based study

Randomized trial of leuprolide versus continuous oral contraceptives in the treatment of endometriosis-associated pelvic pain David S. Guzick, M.D.,

Rebecca A. Feldman, M. D. , Kathleen O'Neill, M. D. , Samantha F

Peritoneal fluid macrophages in endometriosis: correlation between the expression of estrogen receptors and inflammation Paola Montagna, B.Sc., Silvia.

Elizabeth Taylor, M.D., Christina Williams, M.D.

Oocyte cryopreservation

Increased frequency of human leukocyte antigen–E inhibitory receptor CD94/NKG2A– expressing peritoneal natural killer cells in patients with endometriosis

Endometriosis and pregnancy complications: a Danish cohort study

Influence of acupuncture stimulation on pregnancy rates for women undergoing embryo transfer Caroline Smith, Ph.D., Meaghan Coyle, B.Hlth.Sc. (Acup.),

Rahi Victory, M. D. , F. R. C. S. C. , Ghassan M. Saed, Ph. D

Vascular endothelial growth factor polymorphisms (−460C/T, +405G/C, and 936C/T) and endometriosis: their influence on vascular endothelial growth factor expression

Management of tubal ectopic pregnancy: methotrexate and salpingostomy are preferred to preserve fertility Stephanie Beall, M.D., Ph.D., Alan H. DeCherney,

Imbalance in the peritoneal levels of interleukin 1 and its decoy inhibitory receptor type II in endometriosis women with infertility and pelvic pain

Clomiphene citrate at 50: the dawning of assisted reproduction

Peritoneal cytokines and adhesion formation in endometriosis: an inverse association with vascular endothelial growth factor concentration Ewa Barcz,

Introduction Fertility and Sterility

Akanksha Mehta, M.D., Darius A. Paduch, M.D., Ph.D.

Changes in cytokine levels of patients with ovarian endometriosis after treatment with gonadotropin-releasing hormone analogue, ultrasound-guided drainage,

Donatella Paoli, B. Sc. , Ph. D. , Mariagrazia Gallo, B. Sc. , Ph. D

Long-term fracture risk among women with proven endometriosis

Antoni J. Duleba, M.D., Ibrahim M. Ahmed, M.D. Fertility and Sterility

Roberto Ensenat-Waser, Ph. D. , Antonio Pellicer, M. D. , Ph. D

Simvastatin improves biochemical parameters in women with polycystic ovary syndrome: results of a prospective, randomized trial Antoni J. Duleba, M.D.,

Website quality assessment: Mistaking apples for oranges

The vitamin E–binding protein afamin is altered significantly in the peritoneal fluid of women with endometriosis Beata E. Seeber, M.D., M.S.C.E., Theresa.

Low serum and peritoneal fluid concentration of interferon-γ–induced protein-10 (CXCL10) in women with endometriosis Letizia Galleri, Ph.D., Stefano.

Pregnancy outcome in infertile patients with polycystic ovary syndrome who were treated with metformin Samuel S. Thatcher, M.D., Ph.D., Elizabeth M.

L. Scott, J. Bernsten, K. DeLegge, J. Hill, N. Ramsing

CD11c+HLADR+ dendritic cells are present in human ovarian follicular fluid, and their maturity correlates with serum estradiol levels in response to gonadotropins

Fertility and Sterility: an evaluation

Impact of subclinical hypothyroidism in women with recurrent early pregnancy loss Lia A. Bernardi, M.D., Ronald N. Cohen, M.D., Mary D. Stephenson, M.D.,

Association of endometriosis with body size and figure

Current evaluation of amenorrhea

David H. Barad, M.D., M.S., Norbert Gleicher, M.D.

Expression of steroid receptors, their cofactors, and aromatase in human luteinized granulosa cells after controlled ovarian hyperstimulation Shiuh Y.

Aline Ketefian, M. D. , Jianfang Hu, Ph. D. , Alfred A. Bartolucci, Ph

Nerve fibers and menstrual cycle in peritoneal endometriosis

In vitro sildenafil citrate use as a sperm motility stimulant

Soluble HLA-G in the peritoneal fluid of women with endometriosis

What’s the delay? A qualitative study of women’s experiences of reaching a diagnosis of endometriosis Karen Ballard, Ph.D., Karen Lowton, Ph.D., Jeremy.

Are sperm DNA fragmentation, hyperactivation, and hyaluronan-binding ability predictive for fertilization and embryo development in in vitro fertilization.

Progesterone level and progesterone/estradiol ratio on the day of hCG administration: detrimental cutoff levels and new treatment strategy Eman A. Elgindy,

Contact among families who share the same sperm donor

P-24 Fertility and Sterility Volume 85, Pages S19-S20 (April 2006)

Maturation of human ovarian follicles is accompanied by a decrease in the CD56+CD16+ natural killer cell population Ofer Fainaru, M.D., Ph.D., Shay Hantisteanu,

Presentation transcript:

Human leukocyte antigen expression by peritoneal macrophages from women with pelvic endometriosis is depressed but coordinated with costimulatory molecule expression Tomoaki Kusume, M.D., Nagamasa Maeda, M.D., Ph.D., Chiaki Izumiya, M.D., Ph.D., Yorito Yamamoto, M.D., Kazutoshi Hayashi, M.D., Ph.D., Hiroyoshi Oguri, M.D., Ph.D., Yoshiko Nishimori, B.Sc., Takao Fukaya, M.D., Ph.D. Fertility and Sterility Volume 83, Issue 4, Pages 1232-1240 (April 2005) DOI: 10.1016/j.fertnstert.2004.11.039 Copyright © 2005 American Society for Reproductive Medicine Terms and Conditions

FIGURE 1 Determination of fluorescence intensities and activation ratios for human leukocyte antigen HLA-DR and CD14 by flow cytometry in women with endometriosis. (A) Peripheral blood (PB) monocytes. (B) Peritoneal fluid (PF) macrophages. Control subjects are shown on the left within each panel. Mean HLA-DR fluorescence intensity among CD14+ HLA-DR+ cells in PF macrophages (b-cont.2) was divided by that in PB monocytes (a-cont.1) as an index of macrophage activation potential (macrophage activation ratio) [(b-cont.2)/(a-cont.1)], as also was done for HLA-ABC and costimulatory molecules. Cont, control. Fertility and Sterility 2005 83, 1232-1240DOI: (10.1016/j.fertnstert.2004.11.039) Copyright © 2005 American Society for Reproductive Medicine Terms and Conditions

FIGURE 2 Correlation between fluorescence intensities of human leukocyte antigen (HLA) and costimulatory molecules on peritoneal macrophages in women with endometriosis. (A) Correlation between HLA-ABC and costimulatory molecules. (B) Correlation between HLA-DR and costimulatory molecules. Correlation was assessed by linear regression analysis. Fertility and Sterility 2005 83, 1232-1240DOI: (10.1016/j.fertnstert.2004.11.039) Copyright © 2005 American Society for Reproductive Medicine Terms and Conditions

FIGURE 3 Correlation between fluorescence intensities of human leukocyte antigen (HLA) and costimulatory molecules on peritoneal macrophages in women without endometriosis. (A) The correlation between HLA-ABC and costimulatory molecules. (B) The correlation between HLA-DR and costimulatory molecules. Correlation was assessed by linear regression analysis. Fertility and Sterility 2005 83, 1232-1240DOI: (10.1016/j.fertnstert.2004.11.039) Copyright © 2005 American Society for Reproductive Medicine Terms and Conditions