Fig. 6. CXM correlates with age and growth velocity.

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Fig. 6. CXM correlates with age and growth velocity. CXM correlates with age and growth velocity. (A) Serum CXM is plotted against age for normally growing infants and children (n = 129). Established height velocity curve averages for males (blue line) and females (red line) are superimposed for comparison. (B) CXM is plotted against age, grouped by sex, and shown as means ± SE. Sex-matched velocity norms for males and females are superimposed as before. (C) Infants and children 0.18 to 16 years of age were measured for length/height and assayed for serum CXM at 0-, 6-, and 12-month periods (n = 44). Height velocities were calculated as change in length/height over time interval, converted to centimeter per year, and plotted against CXM [adjusted R2 (weighted) = 0.88, P < 0.001). (D) Log-transformed CXM serum concentrations for normally growing children and nongrowing adults are plotted against age (n = 139). Ryan F. Coghlan et al., Sci Transl Med 2017;9:eaan4669 Published by AAAS