Battling low back pain with novel NP cell models

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In This Issue Cell Volume 145, Issue 3, (April 2011)

General Information Osteoarthritis and Cartilage

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Battling low back pain with novel NP cell models G.G. van den Akker, T.J. Welting, D.A. Surtel, A. Cremers, J.W. Voncken, L.W. van Rhijn Osteoarthritis and Cartilage Volume 21, (April 2013) DOI: 10.1016/j.joca.2013.02.430 Copyright © 2013 Terms and Conditions

Figure 1 NP cell clone characteristics. A) phase contrast images of representative monolayer cultured NP subtypes. Bar indicates 20 microns. B) Gene expression of CA12, FOXF1 and KRT19 in a monolayer differentiation assay. White bars: t=0 ; black bars: t= 7 days differentiation medium (DM). C) Representative responder and non-responder clones were seeded on aggrecan coated plates in combination with control or DM. Fold induction is shown, compared to non adhered cells for: SOX9, COL2A1, AGC1 and COL1A1 is shown. Housekeeper is bActin. Osteoarthritis and Cartilage 2013 21, DOI: (10.1016/j.joca.2013.02.430) Copyright © 2013 Terms and Conditions