David valve-sparing aortic root replacement: Equivalent mid-term outcome for different valve types with or without connective tissue disorder John-Peder.

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Presentation transcript:

David valve-sparing aortic root replacement: Equivalent mid-term outcome for different valve types with or without connective tissue disorder John-Peder Escobar Kvitting, MD, PhD, Fabian A. Kari, MD, Michael P. Fischbein, MD, PhD, David H. Liang, MD, PhD, Anne-Sophie Beraud, MD, Elizabeth H. Stephens, MD, PhD, R. Scott Mitchell, MD, D. Craig Miller, MD The Journal of Thoracic and Cardiovascular Surgery Volume 145, Issue 1, Pages 117-127.e5 (January 2013) DOI: 10.1016/j.jtcvs.2012.09.013 Copyright © 2013 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 A, Distribution of patients undergoing valve-sparing aortic root replacement according to type of aortic valve. B, Age distribution of patients with tricuspid (TAV) and bicuspid aortic valve (BAV). C, Distribution of patients (n, %) with a BAV according to Sievers’ classification. D, Distribution of arch replacement during study period according to valve type. The Journal of Thoracic and Cardiovascular Surgery 2013 145, 117-127.e5DOI: (10.1016/j.jtcvs.2012.09.013) Copyright © 2013 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 A, Kaplan-Meier survival curve for 233 patients undergoing valve-sparing aortic root replacement. B, Kaplan-Meier survival curve of 233 patients undergoing valve-sparing aortic root replacement compared with general US population matched for age, gender, and race. C, Kaplan-Meier survival curves comparing tricuspid (TAV) and bicuspid aortic valve (BAV) subsets. D, Kaplan-Meier survival curves comparing patients with confirmed diagnosis of Marfan syndrome or other connective tissue disorders (CTDs) compared with remainder of patients. Vertical bars represent ± 1 standard error. The Journal of Thoracic and Cardiovascular Surgery 2013 145, 117-127.e5DOI: (10.1016/j.jtcvs.2012.09.013) Copyright © 2013 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 A, Freedom from reoperation on aortic root after valve-sparing aortic root replacement. B, Freedom from reoperation on aortic root comparing tricuspid (TAV) and bicuspid aortic valve (BAV) subsets. C, Freedom from reoperation on aortic root after valve-sparing aortic root replacement comparing patients with confirmed Marfan syndrome or another connective tissue disorder (CTD) and remainder of patient cohort. Vertical bars represent ± 1 standard error. The Journal of Thoracic and Cardiovascular Surgery 2013 145, 117-127.e5DOI: (10.1016/j.jtcvs.2012.09.013) Copyright © 2013 The American Association for Thoracic Surgery Terms and Conditions

Figure E1 A, Freedom from Stanford type B aortic dissection for all patients. B, Freedom from Stanford type B aortic dissection comparing patients with confirmed diagnosis of Marfan syndrome or other connective tissue disorder (CTD) with remainder of patients. C, Freedom from more than 2+ aortic regurgitation. Vertical bars represent ± 1 standard error. The Journal of Thoracic and Cardiovascular Surgery 2013 145, 117-127.e5DOI: (10.1016/j.jtcvs.2012.09.013) Copyright © 2013 The American Association for Thoracic Surgery Terms and Conditions

Figure E2 A, Freedom from structural valve deterioration (SVD) after valve-sparing aortic root replacement. B, Freedom from SVD comparing tricuspid (TAV) and bicuspid aortic valve (BAV) subsets. C, Freedom from SVD comparing patients with confirmed diagnosis of Marfan syndrome or other connective tissue disorder (CTD) and remainder of patients. Vertical bars represent ± 1 standard error. The Journal of Thoracic and Cardiovascular Surgery 2013 145, 117-127.e5DOI: (10.1016/j.jtcvs.2012.09.013) Copyright © 2013 The American Association for Thoracic Surgery Terms and Conditions

Figure E3 A, Freedom from structural valve deterioration comparing patients with 4+ aortic regurgitation (AR) preoperatively and remainder of patients. B, Freedom from reoperation on aortic root comparing patients with 4+ aortic regurgitation preoperatively and remainder of patients. Vertical bars represent ± 1 standard error. The Journal of Thoracic and Cardiovascular Surgery 2013 145, 117-127.e5DOI: (10.1016/j.jtcvs.2012.09.013) Copyright © 2013 The American Association for Thoracic Surgery Terms and Conditions