Growth factors and experimental arterial grafts

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Growth factors and experimental arterial grafts Antonio V. Sterpetti, MD, FACS, FRCS, Sandro Lepidi, MD, Valeria Borrelli, PhD, Luca Di Marzo, MD, Paolo Sapienza, MD, Alessandra Cucina, PhD, Marco Ventura, MD Journal of Vascular Surgery Volume 64, Issue 5, Pages 1444-1449 (November 2016) DOI: 10.1016/j.jvs.2015.07.091 Copyright © 2015 Society for Vascular Surgery Terms and Conditions

Fig 1 A, Histochemical localization of basic fibroblast growth factor (bFGF) in arterial vein grafts explanted 4 weeks after surgery (transverse section): localization of bFGF in smooth muscle cells which form the area of myointimal hyperplasia (MH; original magnification ×400), L, Lumen. B, Histochemical localization of platelet-derived growth factor (PDGF) in arterial vein grafts explanted 4 weeks after surgery (transverse section): localization of PDGF in smooth muscle cells which form the area of MH (original magnification ×400). Journal of Vascular Surgery 2016 64, 1444-1449DOI: (10.1016/j.jvs.2015.07.091) Copyright © 2015 Society for Vascular Surgery Terms and Conditions

Fig 2 Histochemistry for interleukin (IL)-1 in arterial isografts (left) and arterial allografts (right) explanted 4 weeks after surgery (transverse sections). No detectable localization of IL-1 in isografts (left). Evident localization of IL-1 in the area of myointimal hyperplasia (MH) in aortic allografts (original magnification ×200). L, Lumen. Journal of Vascular Surgery 2016 64, 1444-1449DOI: (10.1016/j.jvs.2015.07.091) Copyright © 2015 Society for Vascular Surgery Terms and Conditions

Fig 3 Histochemistry for tumor necrosis factor (TNF)-α in arterial isografts (left) and arterial allografts (right) explanted 4 weeks after surgery (transverse sections). No detectable localization of TNF-α in isografts (left). Evident localization of TNF-α in the area of myoinitmal hyperplasia in aortic allografts (original magnification ×200). L, Lumen. Journal of Vascular Surgery 2016 64, 1444-1449DOI: (10.1016/j.jvs.2015.07.091) Copyright © 2015 Society for Vascular Surgery Terms and Conditions