Early left ventricular regional contractile impairment in chronic mitral regurgitation occurs in a consistent, heterogeneous pattern Hersh S. Maniar,

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Presentation transcript:

Early left ventricular regional contractile impairment in chronic mitral regurgitation occurs in a consistent, heterogeneous pattern Hersh S. Maniar, MD, Beckah D. Brady, BS, Urvi Lee, PhD, Brian P. Cupps, PhD, Julia Kar, PhD, Kathleen M. Wallace, MSW, Michael K. Pasque, MD The Journal of Thoracic and Cardiovascular Surgery Volume 148, Issue 4, Pages 1694-1699 (October 2014) DOI: 10.1016/j.jtcvs.2014.05.088 Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Images from (A and B) end-diastole and (C and D) end-systole, demonstrating deformations of tag lines during systole. The Journal of Thoracic and Cardiovascular Surgery 2014 148, 1694-1699DOI: (10.1016/j.jtcvs.2014.05.088) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 For each patient, the heart was registered to a standard 18-region finite element mesh, and displacements were computed at the intersection points of the tag surfaces. Model-predicted displacements and strains were computed from a least squares fitting of the measured displacement data. The Journal of Thoracic and Cardiovascular Surgery 2014 148, 1694-1699DOI: (10.1016/j.jtcvs.2014.05.088) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 Global left ventricular function, as assessed by global myocardial circumferential and longitudinal strains, compared with normal controls. LV, Left ventricular; MR, mitral regurgitation. The Journal of Thoracic and Cardiovascular Surgery 2014 148, 1694-1699DOI: (10.1016/j.jtcvs.2014.05.088) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

Figure 4 Regional ventricular function among patients with mitral regurgitation, assessed by multiparametric z-score analysis. The Journal of Thoracic and Cardiovascular Surgery 2014 148, 1694-1699DOI: (10.1016/j.jtcvs.2014.05.088) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions