Volume 75, Issue 4, Pages (February 2009)

Slides:



Advertisements
Similar presentations
Acute interstitial nephritis
Advertisements

Quiz Page June 2007 American Journal of Kidney Diseases
Thin Glomerular Basement Membranes
Renal manifestations in Fabry disease and therapeutic options
Propofol-related green urine
The Case | Diabetic nephropathy in a nondiabetic smoker?
Volume 79, Issue 6, Pages (March 2011)
Infection in Renal Transplantation: A Case of Acute Q Fever
Acute interstitial nephritis
Shining light on vitamin D trials in chronic kidney disease
Volume 76, Issue 5, Pages (September 2009)
Volume 66, Issue 1, Pages (July 2004)
The big squeeze: giant cells in granulomatous interstitial nephritis
Volume 80, Issue 10, Pages (November 2011)
Volume 77, Issue 1, Pages 6-8 (January 2010)
Peritubular capillaritis in the renal allograft takes center stage
Volume 77, Issue 9, Pages (May 2010)
Marie Claire Gubler, Corinne Antignac  Kidney International 
Volume 77, Issue 9, Pages (May 2010)
Volume 79, Issue 1, Pages (January 2011)
Volume 70, Issue 8, Pages (October 2006)
Comorbidity and confounding in end-stage renal disease
Atubular glomeruli in a rat model of polycystic kidney disease
Intra-glomerular metastases
Volume 87, Issue 2, Pages (February 2015)
U-shaped effect of eGFR and mortality
The Case ∣ A young man with acute kidney injury after exercise
Volume 70, Issue 12, Pages (December 2006)
The Case ∣ Fever, rash, and positive Ehrlichia antibodies
Nephrology Crossword: History of nephrology
Ferruh Artunc, Friedhelm Hildebrandt, Kerstin Amann 
Volume 85, Issue 6, Pages (June 2014)
Volume 76, Issue 5, Pages (September 2009)
Therapy of relapsing minimal-change disease in adults: a new approach?
An unusual cause of acute renal failure
AJKD Atlas of Renal Pathology: Idiopathic Nodular Sclerosis
Hypertension, race, and glomeruli: more than simply a numbers game
The Case | Idiopathic hypocomplementemic interstitial nephritis
Volume 69, Issue 12, Pages (June 2006)
Volume 69, Issue 3, Pages (February 2006)
Volume 72, Issue 10, Pages (November 2007)
Nephrology Crossword: Glomerulonephritis
Quiz Page November 2006 American Journal of Kidney Diseases
Masahide Yazaki, Sandra A. Farrell, Merrill D. Benson 
Michael W. Steffes, Derek Schmidt, Rebecca Mccrery, John M. Basgen 
Volume 71, Issue 4, Pages (February 2007)
Acute phosphate nephropathy
Fibrosis and renal aging
Volume 73, Issue 9, Pages (May 2008)
H. Raffi, J.M. Bates, Z. Laszik, S. Kumar  Kidney International 
Cardio-Kidney-Damage: a unifying concept
Quiz Page August 2013 American Journal of Kidney Diseases
Quiz American Journal of Kidney Diseases
Volume 80, Issue 10, Pages (November 2011)
Membranous and crescentic glomerulonephritis in a patient with anti-nuclear and anti- neutrophil cytoplasmic antibodies  A. Chang, O. Aneziokoro, S.M.
Is complement a target for therapy in renal disease?
The Case ∣ The eyes have it!
Amylin deposition in the kidney of patients with diabetic nephropathy
Volume 64, Issue 1, Pages (July 2003)
The Case | Peculiar fibrous nodules in a renal transplant biopsy
Volume 68, Issue 5, Pages (November 2005)
Volume 75, Issue 6, Pages (March 2009)
Familial phenotype differences in PKD11
Krishna M. Baradhi, Subhan Ahmed, Malcolm L. Buford 
Unmasking a unique glomerular lesion
Volume 85, Issue 4, Pages (April 2014)
The Ebf1 knockout mouse and glomerular maturation
Acute phosphate nephropathy
Ronen Levi, Justin Silver  Kidney International 
Epidemiologic data of renal diseases from a single unit in China: Analysis based on 13,519 renal biopsies  Lei-Shi Li, Zhi-Hong Liu  Kidney International 
Presentation transcript:

Volume 75, Issue 4, Pages 415-419 (February 2009) Mutations in phospholipase C epsilon 1 are not sufficient to cause diffuse mesangial sclerosis  Rodney D. Gilbert, Claire L.S. Turner, Jane Gibson, Paul S. Bass, Mushfequr R. Haq, Esta Cross, David J. Bunyan, Andrew R. Collins, William J. Tapper, Juliet C. Needell, Beverley Dell, Newton E. Morton, I. Karen Temple, David O. Robinson  Kidney International  Volume 75, Issue 4, Pages 415-419 (February 2009) DOI: 10.1038/ki.2008.573 Copyright © 2009 International Society of Nephrology Terms and Conditions

Figure 1 Extract of the extended pedigree of the affected kindred. Kidney International 2009 75, 415-419DOI: (10.1038/ki.2008.573) Copyright © 2009 International Society of Nephrology Terms and Conditions

Figure 2 Light microscopy of renal biopsies (silver stain). (a) Biopsy taken from individual 3 at 15 months of age. (b) Biopsy from individual 19 at 5 months of age. (c) Biopsy from individual 4 taken at 12 months of age. All biopsies show prominence of the mesangial matrix and podocytes with varying degrees of glomerular sclerosis and tubulointerstitial fibrosis. All stained with Jones' silver stain. Original magnification × 200. Kidney International 2009 75, 415-419DOI: (10.1038/ki.2008.573) Copyright © 2009 International Society of Nephrology Terms and Conditions

Figure 3 DNA sequence analysis of exon 3 of the PLCE1 gene. (a) Sequencing data for bases 1293–1313 of exon 3 of the PLCE1 gene in a normal individual. (b) Sequencing data of an affected member of the pedigree showing deletion of bases 1303–1306. (c) Interpretation of sequence data indicating AGGA deletion (bold) and generation of the translational termination codon TAA (underlined). Kidney International 2009 75, 415-419DOI: (10.1038/ki.2008.573) Copyright © 2009 International Society of Nephrology Terms and Conditions