Sole-Searing Pain: Classic Kaposi's Sarcoma

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Sole-Searing Pain: Classic Kaposi's Sarcoma Daniel J. Minter, BS, Prashant Kotwani, MD, Lucinda L. Kohn, MD, Toby Maurer, MD, Andrew R. Lai, MD, MPH The American Journal of Medicine Volume 130, Issue 11, Pages 1262-1264 (November 2017) DOI: 10.1016/j.amjmed.2017.06.014 Copyright © 2017 Elsevier Inc. Terms and Conditions

Figure 1 (A) This is what the patient's foot looked like during the index admission. The thickened skin denotes retention hyperkeratosis, which is a result of lymphedema. (B) Roughly 2 months after initiation of therapy with Unna boot compression, the patient reported marked improvement in pain and swelling. Hyperkeratosis remained. The American Journal of Medicine 2017 130, 1262-1264DOI: (10.1016/j.amjmed.2017.06.014) Copyright © 2017 Elsevier Inc. Terms and Conditions

Figure 2 Dermatopathology of the skin biopsy demonstrated Kaposi's sarcoma infiltrating the upper dermis. (A) The findings are shown at low magnification (hematoxylin and eosin stain). (B) The findings are shown at high magnification (hematoxylin and eosin stain). (C) Immunohistochemistry revealed positive staining for human herpesvirus 8 in select nuclei (immunostaining). The American Journal of Medicine 2017 130, 1262-1264DOI: (10.1016/j.amjmed.2017.06.014) Copyright © 2017 Elsevier Inc. Terms and Conditions