Prevalence of CXCR4-tropic viruses in clustered transmission chains at the time of primary HIV-1 infection  P. Frange, L. Meyer, J. Ghosn, C. Deveau, C. Goujard, C. Duvivier, R. Tubiana, C. Rouzioux, M.-L. Chaix  Clinical Microbiology and Infection  Volume 19, Issue 5, Pages E252-E255 (May 2013) DOI: 10.1111/1469-0691.12127 Copyright © 2013 European Society of Clinical Infectious Diseases Terms and Conditions

Fig. 1 Evolutionary relationships of the 65 HIV-1 reverse transcriptase genes involved in clustered transmissions. Viruses isolated from women (o), men infected through heterosexual intercourse (▪) and patients (all were men) infected through unknown intercourse (▾) were represented. The evolutionary history was inferred using the neighbour-joining method [12]. The optimal tree with the sum of branch length = 1.01415652 is shown. The tree is drawn to scale, with branch length in the same units as those of the evolutionary distances used to infer the phylogenetic tree. The evolutionary distances were computed using the maximum composite likelihood method [13] and are in the units of the number of base substitutions per site. Codon positions included were 1st+2nd+3rd+noncoding. All positions containing gaps and missing data were eliminated from the dataset. There were a total of 433 positions in the final dataset. Phylogenetic analyses were conducted in MEGA4 [14]. Clinical Microbiology and Infection 2013 19, E252-E255DOI: (10.1111/1469-0691.12127) Copyright © 2013 European Society of Clinical Infectious Diseases Terms and Conditions