In vivo structural analysis of subchondral trabecular bone in osteoarthritis of the hip using multi-detector row CT K. Chiba, M. Ito, M. Osaki, M. Uetani,

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In vivo structural analysis of subchondral trabecular bone in osteoarthritis of the hip using multi-detector row CT K. Chiba, M. Ito, M. Osaki, M. Uetani, H. Shindo Osteoarthritis and Cartilage Volume 19, Issue 2, Pages 180-185 (February 2011) DOI: 10.1016/j.joca.2010.11.002 Copyright © 2010 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 3D reconstructed MDCT image of a normal hip joint. The principal compressive trabeculae of the femoral head and corresponding acetabular trabeculae are well demonstrated, although the others are not clear because of insufficient spatial resolution. Osteoarthritis and Cartilage 2011 19, 180-185DOI: (10.1016/j.joca.2010.11.002) Copyright © 2010 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 ROI for the bone microstructure analysis. The subchondral trabecular bone structure of the acetabulum and femoral head and the joint space volume were measured. The subchondral bone region is a 2×2cm2 area, 1cm under the subchondral endplate, and aligned with the principal compressive trabeculae. Osteoarthritis and Cartilage 2011 19, 180-185DOI: (10.1016/j.joca.2010.11.002) Copyright © 2010 Osteoarthritis Research Society International Terms and Conditions

Fig. 3 Relationship between joint space volume and app Tb.Th of femoral head subchondral bone. There is a negative correlation between joint space volume and app Tb.Th. (r=−0.665, P<0.001). App Tb.Th increases in early and advanced staged OA, but not in dysplasia. Osteoarthritis and Cartilage 2011 19, 180-185DOI: (10.1016/j.joca.2010.11.002) Copyright © 2010 Osteoarthritis Research Society International Terms and Conditions

Fig. 4 3D reconstructed MDCT images of femoral head subchondral trabecular bone of a normal subject (A) and an advanced OA patient (B). The subchondral trabecular bone of the OA patient shows mass formation by thick trabecular bones. Osteoarthritis and Cartilage 2011 19, 180-185DOI: (10.1016/j.joca.2010.11.002) Copyright © 2010 Osteoarthritis Research Society International Terms and Conditions