The impact of lymph node station on survival in 348 patients with surgically resected malignant pleural mesothelioma: Implications for revision of the.

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Presentation transcript:

The impact of lymph node station on survival in 348 patients with surgically resected malignant pleural mesothelioma: Implications for revision of the American Joint Committee on Cancer staging system Raja M. Flores, MD, Tom Routledge, MD, Venkatraman E. Seshan, PhD, Joseph Dycoco, BA, Maureen Zakowski, MD, Yael Hirth, Valerie W. Rusch, MD The Journal of Thoracic and Cardiovascular Surgery Volume 136, Issue 3, Pages 605-610 (September 2008) DOI: 10.1016/j.jtcvs.2008.02.069 Copyright © 2008 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 A, Distribution of positive node stations: left lung. Most patients who had lymph node metastases had more than 1 nodal station involved, so the number of metastatic sites exceeds the number of resections. B, Distribution of positive node stations: right lung. Most patients who had lymph node metastases had more than 1 nodal station involved, so the number of metastatic sites exceeds the number of resections. The Journal of Thoracic and Cardiovascular Surgery 2008 136, 605-610DOI: (10.1016/j.jtcvs.2008.02.069) Copyright © 2008 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Overall survival of patients with N0, N1(+) versus N2(+), N2/N1(+) and internal thoracic(+) nodal disease. The Journal of Thoracic and Cardiovascular Surgery 2008 136, 605-610DOI: (10.1016/j.jtcvs.2008.02.069) Copyright © 2008 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 Overall survival of patients with N1 only versus N2 only nodal disease. The Journal of Thoracic and Cardiovascular Surgery 2008 136, 605-610DOI: (10.1016/j.jtcvs.2008.02.069) Copyright © 2008 The American Association for Thoracic Surgery Terms and Conditions

Figure 4 Overall survival of patients with N1/N2 versus N2 only nodal metastases. The Journal of Thoracic and Cardiovascular Surgery 2008 136, 605-610DOI: (10.1016/j.jtcvs.2008.02.069) Copyright © 2008 The American Association for Thoracic Surgery Terms and Conditions

Figure 5 Overall survival of patients with 0, 1, and 2 or more nodal stations involved. The Journal of Thoracic and Cardiovascular Surgery 2008 136, 605-610DOI: (10.1016/j.jtcvs.2008.02.069) Copyright © 2008 The American Association for Thoracic Surgery Terms and Conditions

Figure 6 Overall survival of patients by T stage. The Journal of Thoracic and Cardiovascular Surgery 2008 136, 605-610DOI: (10.1016/j.jtcvs.2008.02.069) Copyright © 2008 The American Association for Thoracic Surgery Terms and Conditions