Towards an Individualized Delineation of Functional Neuroanatomy

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Towards an Individualized Delineation of Functional Neuroanatomy Theodore D. Satterthwaite, Christos Davatzikos Neuron Volume 87, Issue 3, Pages 471-473 (August 2015) DOI: 10.1016/j.neuron.2015.07.009 Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure 1 Schematic of the Single-Subject Approach (A) Typical approach to parcellation using group-average data. In prior studies, data from a group of many individual participants is averaged to create a parcellation that delineates patterns of functional neuroanatomy. However, because group-average data across dozens of participants is used, this parcellation necessarily reflects common functional neuroanatomical features present across individuals. (B) Single-participant approach used by Laumann et al. (2015). In this approach, one individual was scanned repeatedly, resulting in 14 hr of data. This data was then used to create a detailed functional parcellation that delineates the detailed functional neuroanatomy of that individual. Results show commonalities with the group-level parcellation but also reveal replicable, fine-grained differences that are present only in the individual. Neuron 2015 87, 471-473DOI: (10.1016/j.neuron.2015.07.009) Copyright © 2015 Elsevier Inc. Terms and Conditions