Effect of epinephrine on epidural, intrathecal, and plasma pharmacokinetics of ropivacaine and bupivacaine in sheep M. Ratajczak-Enselme, J.-P. Estebe,

Slides:

Advertisements

Similar presentations

Human factors in anaesthesia: lessons from aviation

Advertisements

Pharmacokinetic profile of epidurally administered methylnaltrexone, a novel peripheral opioid antagonist in a rabbit model D.B. Murphy, H. El Behiery,

Reversal of rocuronium-induced (1

R.J. Parker, I.J. Rechner, T.J. Parke British Journal of Anaesthesia

Parkinson's disease and anaesthesia

S. Bose, Z. Ali, G.P. Rath, H. Prabhakar

Coronary artery bypass grafting in the awake patient combining high thoracic epidural and femoral nerve block: first series of 15 patients N. Noiseux,

I.I. Siempos, K.Z. Vardakas, M.E. Falagas

HES 130/0. 42 shows less alteration of pharmacokinetics than HES 200/0

Topical anaesthesia of the airway using Trachlight™ and MADgic® atomizer in patients with predicted difficult tracheal intubation F.S. Xue, Q.Y. Yang,

A different use of visual analytic techniques in anaesthetics

Controlled comparison between betamethasone gel and lidocaine jelly applied over tracheal tube to reduce postoperative sore throat, cough, and hoarseness.

Long-term functional outcome and performance status after intensive care unit re- admission: a prospective survey N. Conlon, B. O'Brien, G.P. Herbison,

Intrathecal ropivacaine for total hip arthroplasty: double-blind comparative study with isobaric 7.5 mg ml−1 and 10 mg ml−1 solutions D.A. McNamee, L.

Intraoperative thoracic epidural anaesthesia attenuates stress-induced immunosuppression in patients undergoing major abdominal surgery† O. Ahlers, I.

Prevalence of anaemia before major joint arthroplasty and the potential impact of preoperative investigation and correction on perioperative blood transfusions

Electrocardiographic alterations during intravascular application of three different test doses of bupivacaine and epinephrine: experimental study in.

Spinal anaesthesia: comparison of plain ropivacaine 5 mg ml−1 with bupivacaine 5 mg ml−1 for major orthopaedic surgery D.A. McNamee, A.M. McClelland,

Neuromuscular junction in health and disease

J.B. Whiteside, D Burke, J.A.W. Wildsmith

W. Ruppen, L. A. Steiner, J. Drewe, L. Hauenstein, S. Brugger, M. D

Do team processes really have an effect on clinical performance

Faster wash-out and recovery for desflurane vs sevoflurane in morbidly obese patients when no premedication is used L. La Colla, A. Albertin, G. La Colla,

Epidural analgesia compared with peripheral nerve blockade after major knee surgery: a systematic review and meta-analysis of randomized trials S.J.

Population pharmacokinetics of the two enantiomers of tramadol and O-demethyl tramadol after surgery in children F. Bressolle, A. Rochette, S. Khier,

K Haiying British Journal of Anaesthesia

Contralateral effect of amitriptyline and bupivacaine for sciatic nerve block in an animal model of inflammation Estebe J.-P. , Gentili M.E. , Le Corre.

Safety and tolerability of single intravenous doses of sugammadex administered simultaneously with rocuronium or vecuronium in healthy volunteers G Cammu,

Use of an anaesthesia workstation barrier device to decrease contamination in a simulated operating room S Hunter, D Katz, A Goldberg, H.-M. Lin, R Pasricha,

G. Park, M. Lane, S. Rogers, P. Bassett British Journal of Anaesthesia

Anaesthesia for awake craniotomy—evolution of a technique that facilitates awake neurological testing A. Sarang, J. Dinsmore British Journal of Anaesthesia

Sugammadex rapidly reverses moderate rocuronium- or vecuronium-induced neuromuscular block during sevoflurane anaesthesia: a dose–response relationship

FastrachTM tubes: modifying the design for use with the LMA CTrachTM?

Comparison of 1% and 2% lidocaine epidural anaesthesia combined with sevoflurane general anaesthesia utilizing a constant bispectral index A Shono, S.

H.E. Schulenburg, C. Sri-Chandana, G. Lyons, M.O. Columb, H.A. McLure

Spinal anaesthesia: a comparison of plain ropivacaine 5 mg ml−1 with bupivacaine 5 mg ml−1 for major orthopaedic surgery T.M. Cook, D.A. McNamee, K.R.

S.G. Hillyard, T.E. Bate, T.B. Corcoran, M.J. Paech, G. O'Sullivan

Interstitial muscle concentrations of rocuronium under steady-state conditions in anaesthetized dogs: actual versus predicted values Ezzine S. , Varin.

Reviewer Acknowledgment

Effects of ultrasound guidance on the minimum effective anaesthetic volume required to block the femoral nerve A. Casati, M. Baciarello, S. Di Cianni,

H Viitanen, P Annila British Journal of Anaesthesia

Effectiveness of continuous wound infusion of 0

O. Tirel, E. Wodey, R. Harris, J.Y. Bansard, C. Ecoffey, L. Senhadji

S. Caron, J. Berton, L. Beydon British Journal of Anaesthesia

The effect of ephedrine on intubating conditions and haemodynamics during rapid tracheal intubation using propofol and rocuronium M.D. Gopalakrishna,

T.G. Hansen, K.F. Ilett, S.I. Lim, C. Reid, L.P. Hackett, R. Bergesio

H. Schlotterbeck, R. Schaeffer, W. A. Dow, Y. Touret, S. Bailey, P

G.B. Drummond, B. Lafferty British Journal of Anaesthesia

Comparative total and unbound pharmacokinetics of cefazolin administered by bolus versus continuous infusion in patients undergoing major surgery: a randomized.

Teamwork, communication, and anaesthetic assistance in Scotland

Epidural analgesia with 0. 15% ropivacaine plus sufentanil 0

Diffusion of nitrous oxide into the pleural cavity†

M.D. Esler, J. Durbridge, S. Kirby British Journal of Anaesthesia

Effect of i.v. phenylephrine or ephedrine on the ED50 of intrathecal bupivacaine with fentanyl for Caesarean section M.C. Hennebry, G.M. Stocks, P. Belavadi,

Effects of epinephrine and phosphodiesterase III inhibitors on bupivacaine-induced myocardial depression in guinea-pig papillary muscle M. Azuma, M.

J. Bromilow, T. Corcoran British Journal of Anaesthesia

Comparison of ropivacaine 0. 5% (in glucose 5%) with bupivacaine 0

Effect of age on the clinical profile and systemic absorption and disposition of levobupivacaine after epidural administration Simon M.J.G. , Veering.

I.V. ropivacaine compared with lidocaine for the treatment of tinnitus

Cervical epidural analgesia in current anaesthesia practice: systematic review of its clinical utility and rationale, and technical considerations H.

Grand mal convulsion and plasma concentrations after intravascular injection of ropivacaine for axillary brachial plexus blockade M. Mu¨ller, R.J. Litz,

M. J. Sheen, S. -T. Ho, C. -H. Lee, Y. -C. Tsung, F. -L. Chang, S. -T

Epinephrine and clonidine do not improve intrathecal sufentanil analgesia after total hip replacement† R. Fournier, E. Van Gessel, A. Weber, Z. Gamulin

E. C. Hessian, B. E. Evans, J. A. Woods, D. J. Taylor, E Kinkel, A. R

Effect of body mass index on the ED50 volume of bupivacaine 0

Minimum effective local anaesthetic dose of isobaric levobupivacaine and ropivacaine administered via a spinal catheter for hip replacement surgery Sell.

Effect of concentration of local anaesthetic solution on the ED50 of bupivacaine for supraclavicular brachial plexus block† P.K. Gupta, P.M. Hopkins

Plasma lidocaine concentrations following insertion of 2% lidocaine gel into the uterine cavity after uterine balloon thermal ablation G.F. Rousseau,

Kotb H. I. M. , El-Kady S. A. , Emara S. E. S. , Fouad E. A

High plasma ropivacaine concentrations after fascia iliaca compartment block in children Paut O , Schreiber E , Lacroix F , Meyrieux V , Simon N , Lavrut.

Presentation transcript:

Effect of epinephrine on epidural, intrathecal, and plasma pharmacokinetics of ropivacaine and bupivacaine in sheep M. Ratajczak-Enselme, J.-P. Estebe, F.-X. Rose, E. Wodey, J.-M. Malinovsky, F. Chevanne, G. Dollo, C. Ecoffey, P. Le Corre British Journal of Anaesthesia Volume 99, Issue 6, Pages 881-890 (December 2007) DOI: 10.1093/bja/aem291 Copyright © 2007 British Journal of Anaesthesia Terms and Conditions

Fig 1 Experimental protocol for the study. British Journal of Anaesthesia 2007 99, 881-890DOI: (10.1093/bja/aem291) Copyright © 2007 British Journal of Anaesthesia Terms and Conditions

Fig 2 Mean (bold) and individual concentration–time profiles in epidural space after epidural administration of ropivacaine (50 mg) and bupivacaine (30 mg) with and without epinephrine. British Journal of Anaesthesia 2007 99, 881-890DOI: (10.1093/bja/aem291) Copyright © 2007 British Journal of Anaesthesia Terms and Conditions

Fig 3 Mean (bold) and individual concentration–time profiles in intrathecal space after epidural administration of ropivacaine (50 mg) and bupivacaine (30 mg) with and without epinephrine. British Journal of Anaesthesia 2007 99, 881-890DOI: (10.1093/bja/aem291) Copyright © 2007 British Journal of Anaesthesia Terms and Conditions

Fig 4 Mean (bold) and individual concentration–time profiles in plasma after epidural administration of ropivacaine (50 mg) and bupivacaine (30 mg) with and without epinephrine. British Journal of Anaesthesia 2007 99, 881-890DOI: (10.1093/bja/aem291) Copyright © 2007 British Journal of Anaesthesia Terms and Conditions