Leiomyomatous Hamartoma of the Posterior Mediastinum

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Presentation transcript:

Leiomyomatous Hamartoma of the Posterior Mediastinum Benoit Jacques Bibas, MD, Ricardo Mingarini Terra, MD, Angelo Fernandez, MD, Christina Shiang, MD, Paulo Manuel Pêgo-Fernandes, MD, Fabio Biscegli Jatene, MD The Annals of Thoracic Surgery Volume 89, Issue 1, Pages 304-305 (January 2010) DOI: 10.1016/j.athoracsur.2009.06.046 Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Computed tomography of the thorax shows a well-defined mass measuring 9.5 × 4.0 × 3.0 cm located in the right costovertebral region. The vascular supply (arrow) to the mass has its origin in the mediastinum. The Annals of Thoracic Surgery 2010 89, 304-305DOI: (10.1016/j.athoracsur.2009.06.046) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 (A) Histology specimens show smooth muscle proliferation around slit-like spaces lined by pneumocytes. Intraalveolar respiratory macrophages are also seen (hematoxylin-eosin stain, original magnification ×200). (B) Clefts are lined by respiratory-type epithelium (hematoxylin-eosin stain, original magnification ×200). (C) Immunohistochemistry shows thyroid transcription factor-1 positivity in the alveolar-like space lining (original magnification ×200). (D) Strong positivity for desmin in the spindle cell proliferation (original magnification ×100). The Annals of Thoracic Surgery 2010 89, 304-305DOI: (10.1016/j.athoracsur.2009.06.046) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions