International Journal of Cardiology

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International Journal of Cardiology Aldosterone Pathway Blockade to Prevent Atrial Fibrillation: A Systematic Review and Meta-Analysis J. Neefs, N.W.E. van den Berg, J. Limpens, W.R. Berger, S.M. Boekholdt, P. Sanders, J.R. de Groot International Journal of Cardiology Volume 231, Pages 155-161 (March 2017) DOI: 10.1016/j.ijcard.2016.12.029 Copyright © 2017 The Authors Terms and Conditions

International Journal of Cardiology 2017 231, 155-161DOI: (10. 1016/j International Journal of Cardiology 2017 231, 155-161DOI: (10.1016/j.ijcard.2016.12.029) Copyright © 2017 The Authors Terms and Conditions

Fig. 1 Flowchart of study selection. CENTRAL: The Cochrane Central Register of Controlled Trails. International Journal of Cardiology 2017 231, 155-161DOI: (10.1016/j.ijcard.2016.12.029) Copyright © 2017 The Authors Terms and Conditions

Fig. 2 Forest plot of the meta-analysis of AF incidence and MRA treatment, including number of patients with AF during follow-up in the MRA and no MRA arm, with the calculated relative risk reduction. CI: Confidence interval. RRR: relative risk reduction. International Journal of Cardiology 2017 231, 155-161DOI: (10.1016/j.ijcard.2016.12.029) Copyright © 2017 The Authors Terms and Conditions

Fig. 3 Forest plot of meta-analysis of MRA treatment per subgroup: new-onset AF, POAF, recurrence of AF or AF in patients with heart failure. CI: Confidence interval. International Journal of Cardiology 2017 231, 155-161DOI: (10.1016/j.ijcard.2016.12.029) Copyright © 2017 The Authors Terms and Conditions