Virus-specific T cell responses are detected in all MERS survivors.

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Presentation transcript:

Virus-specific T cell responses are detected in all MERS survivors. Virus-specific T cell responses are detected in all MERS survivors. PBMCs from healthy donors and MERS patients were stimulated with MERS-CoV structural protein–specific peptide pools for 12 hours in the presence of brefeldin A. Frequencies of MERS-CoV–specific CD4+ (A and B) and CD8+ (C and D) T cells (determined by IFN-γ intracellular staining) are shown. (E) Summary of total T cell responses against all four peptide pools is shown. (F) Relationship between T cell and neutralizing antibody responses is shown. Jingxian Zhao et al. Sci. Immunol. 2017;2:eaan5393 Copyright © 2017 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works