Mitral Valve Repair for Degenerative Disease: A 20-Year Experience

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Mitral Valve Repair for Degenerative Disease: A 20-Year Experience Mani A. Daneshmand, MD, Carmelo A. Milano, MD, J. Scott Rankin, MD, Emily F. Honeycutt, MBI, Madhav Swaminathan, MD, Linda K. Shaw, MS, Peter K. Smith, MD, Donald D. Glower, MD The Annals of Thoracic Surgery Volume 88, Issue 6, Pages 1828-1837 (December 2009) DOI: 10.1016/j.athoracsur.2009.08.008 Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Frequency per year of mitral valve repair versus mitral replacement for degenerative disease at Duke University from 1986 through 2006. The Annals of Thoracic Surgery 2009 88, 1828-1837DOI: (10.1016/j.athoracsur.2009.08.008) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 (A) Unadjusted Kaplan-Meier survival curves. (B) Survival curves for groups 1 and 2, after Cox model statistical adjustment for differences in baseline characteristics. The Annals of Thoracic Surgery 2009 88, 1828-1837DOI: (10.1016/j.athoracsur.2009.08.008) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Unadjusted Kaplan-Meier survival curves for patients older than and younger than 65 years of age, stratified by valve repair versus replacement. The Annals of Thoracic Surgery 2009 88, 1828-1837DOI: (10.1016/j.athoracsur.2009.08.008) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Unadjusted (A) and adjusted (B) survival curves for repair versus mechanical valve replacement versus tissue valve replacement. No statistical comparison was performed because of concerns about the small sample size of tissue valves, but the trend is apparent. The Annals of Thoracic Surgery 2009 88, 1828-1837DOI: (10.1016/j.athoracsur.2009.08.008) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

Fig 5 Observed survival of propensity-matched quintiles during 15 years of follow-up. Quintile 5 has the greatest propensity for replacement (red), and 1 has the greatest propensity for repair (green). Late survival was better with repair in all quintiles (p = 0.046). The Annals of Thoracic Surgery 2009 88, 1828-1837DOI: (10.1016/j.athoracsur.2009.08.008) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions