Erythromycin improves gastric emptying half-time in adult cystic fibrosis patients with gastroparesis Adriano R. Tonelli, Walter E. Drane, Dennis P. Collins, Wanda Nichols, Veena B. Antony, Eric L. Olson Journal of Cystic Fibrosis Volume 8, Issue 3, Pages 193-197 (May 2009) DOI: 10.1016/j.jcf.2009.02.001 Copyright © 2009 Elsevier B.V. Terms and Conditions
Fig. 1 Gastric emptying scintigraphy with decay correction. In patient 1 the gastric emptying half-time was more than 300 min. IV metoclopramide (Reglan®) was given at 75 min and IV erythromycin administered at 95 min, decreasing the half-time to 60 and 5 min respectively. In patient 2 gastric emptying half-time was 270 min that decreased to 16 min after the administration of IV erythromycin at 82 min of the test. In patient 3 the half-time decreased from 179 min to 10 min after administration of IV erythromycin at 76 min of the test. In patient 4 the half-time decreased from 100 min to 20 min after administration of IV erythromycin at 76 min of the test. In patient 5 the half-time decreased from 108 min to 10 min after the administration of IV erythromycin at 75 min of the study. T1/2: gastric emptying half-time, Erythro: erythromycin. Journal of Cystic Fibrosis 2009 8, 193-197DOI: (10.1016/j.jcf.2009.02.001) Copyright © 2009 Elsevier B.V. Terms and Conditions