HapLogic: A Predictive Human Leukocyte Antigen–Matching Algorithm to Enhance Rapid Identification of the Optimal Unrelated Hematopoietic Stem Cell Sources.

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Presentation transcript:

HapLogic: A Predictive Human Leukocyte Antigen–Matching Algorithm to Enhance Rapid Identification of the Optimal Unrelated Hematopoietic Stem Cell Sources for Transplantation  Jason Dehn, Michelle Setterholm, Kelly Buck, Jane Kempenich, Beth Beduhn, Loren Gragert, Abeer Madbouly, Stephanie Fingerson, Martin Maiers  Biology of Blood and Marrow Transplantation  Volume 22, Issue 11, Pages 2038-2046 (November 2016) DOI: 10.1016/j.bbmt.2016.07.022 Copyright © 2016 The American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 (A) HapLogic search report guide for URD. (B) HapLogic search report guide for UCB. Biology of Blood and Marrow Transplantation 2016 22, 2038-2046DOI: (10.1016/j.bbmt.2016.07.022) Copyright © 2016 The American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 (A) HapLogic search report guide for URD. (B) HapLogic search report guide for UCB. Biology of Blood and Marrow Transplantation 2016 22, 2038-2046DOI: (10.1016/j.bbmt.2016.07.022) Copyright © 2016 The American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 2 Primary data example. Biology of Blood and Marrow Transplantation 2016 22, 2038-2046DOI: (10.1016/j.bbmt.2016.07.022) Copyright © 2016 The American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 3 HLA-A, -B, -C, -DRB1, -DQB1 locus match grade and primary data definitions. Biology of Blood and Marrow Transplantation 2016 22, 2038-2046DOI: (10.1016/j.bbmt.2016.07.022) Copyright © 2016 The American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 4 HapLogic predicted versus observed match rate for 10/10-allele matching. Biology of Blood and Marrow Transplantation 2016 22, 2038-2046DOI: (10.1016/j.bbmt.2016.07.022) Copyright © 2016 The American Society for Blood and Marrow Transplantation Terms and Conditions

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