Volume 30, Issue 2, Pages 171-173 (February 2009) Turnabout Is Fair Play: T Cell Stimulation by Dendritic Cell-Expressed CD40L  David F. Tough  Immunity  Volume 30, Issue 2, Pages 171-173 (February 2009) DOI: 10.1016/j.immuni.2009.01.002 Copyright © 2009 Elsevier Inc. Terms and Conditions

Figure 1 Costimulation of CTL Priming by DC-Expressed CD40L DC can be stimulated to express CD40L by viruses, which may be triggered by the recognition of viral nucleic acids by TLRs. CD8+ T cells responding to their specific peptide ligand are activated to express CD40, and binding of CD40 to CD40L on the DCs promotes CTL priming. Immunity 2009 30, 171-173DOI: (10.1016/j.immuni.2009.01.002) Copyright © 2009 Elsevier Inc. Terms and Conditions