Fetal Adenocarcinoma of the Lung in a 25-Year-Old Woman

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Presentation transcript:

Fetal Adenocarcinoma of the Lung in a 25-Year-Old Woman Marina Longo, MD, Matteo Giaj Levra, MD, Enrica Capelletto, MD, Andrea Billè, MD, Francesco Ardissone, MD, Ubaldo Familiari, MD, Silvia Novello, MD, PhD Journal of Thoracic Oncology Volume 3, Issue 4, Pages 441-443 (April 2008) DOI: 10.1097/JTO.0b013e318169cd9a Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 1 The chest computed tomographic scan shows a homogeneous well-defined perihilar mass without calcification in the right upper lobe. Journal of Thoracic Oncology 2008 3, 441-443DOI: (10.1097/JTO.0b013e318169cd9a) Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 2 Baseline CT scan of the chest. Journal of Thoracic Oncology 2008 3, 441-443DOI: (10.1097/JTO.0b013e318169cd9a) Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 3 Intraoperative specimen. Fragmented mass with encephaloid features. Journal of Thoracic Oncology 2008 3, 441-443DOI: (10.1097/JTO.0b013e318169cd9a) Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 4 Fetal adenocarcinoma of the lung. At low magnification a growth of densely packed irregular glands, lined by columnar cells, in a cellular stroma is observed. Journal of Thoracic Oncology 2008 3, 441-443DOI: (10.1097/JTO.0b013e318169cd9a) Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 5 Fetal adenocarcinoma of the lung. Irregular glands are observed in a cellular pattern lacking atypia and made of elongated cells with bland nuclei. The glands are lined by columnar cells, with a basal partially polarized nucleus and scant mucinous cytoplasm. A central nest of squamoid looking cells is present. Journal of Thoracic Oncology 2008 3, 441-443DOI: (10.1097/JTO.0b013e318169cd9a) Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions