Immunofluorescence on pronase-digested paraffin sections: A valuable salvage technique for renal biopsies S.H. Nasr, S.J. Galgano, G.S. Markowitz, M.B.

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Immunofluorescence on pronase-digested paraffin sections: A valuable salvage technique for renal biopsies S.H. Nasr, S.J. Galgano, G.S. Markowitz, M.B. Stokes, V.D. D'Agati Kidney International Volume 70, Issue 12, Pages 2148-2151 (December 2006) DOI: 10.1038/sj.ki.5001990 Copyright © 2006 International Society of Nephrology Terms and Conditions

Figure 1 IF findings in pronase-digested paraffin tissue. (a) Granular global glomerular capillary wall positivity for IgG in a case of MGN. (b) Global mesangial positivity for IgA in a case of IgAN. (c) Intracapillary protein thrombi staining strongly for IgM in a case of cryoglobulinemic glomerulonephritis. (d) ‘Smudgy’ mesangial deposits of kappa in a patient with primary amyloidosis, AL kappa type. (e) Linear tubular basement membrane deposits of kappa light chain in a case of kappa light-chain deposition disease. (f) Intracellular proximal tubular crystals of kappa light chain in a case of kappa LCFS. (a–f) Original magnification × 400. Kidney International 2006 70, 2148-2151DOI: (10.1038/sj.ki.5001990) Copyright © 2006 International Society of Nephrology Terms and Conditions