Randomized long-term evaluation of bicarbonate-buffered CAPD solution

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Randomized long-term evaluation of bicarbonate-buffered CAPD solution Mariano Feriani, Judith Kirchgessner, Giuseppe La Greca, Jutta Passlick-Deetjen Kidney International Volume 54, Issue 5, Pages 1731-1738 (November 1998) DOI: 10.1046/j.1523-1755.1998.00167.x Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 1 Time course of arterial plasma bicarbonate concentration during the study (▪ lactate, N = 32; ▴ bicarbonate, N = 33). Kidney International 1998 54, 1731-1738DOI: (10.1046/j.1523-1755.1998.00167.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 2 Arterial plasma bicarbonate concentration differences from baseline. Symbols are: lactate, dotted line; bicarbonate, solid line. During week 12, lactate = 0.11 ± 2.21mmol/liter, bicarbonate 1.69 ± 2.55mmol/liter P < 0.05, 95% confidence interval for the difference 0.21 to 2.94mmol/liter (lactate, N = 26; bicarbonate, N = 25). During week 24, lactate = 0.03 ± 2.48mmol/liter, bicarbonate 1.82 ± 2.96mmol/liter, P < 0.05, 95% confidence interval for the difference 0.16 to 3.42mmol/liter (lactate N = 23, bicarbonate N = 24). Kidney International 1998 54, 1731-1738DOI: (10.1046/j.1523-1755.1998.00167.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 3 Daily protein catabolic rate normalized to body weight (nPCR) differences from baseline. Symbols are: lactate, dotted line; bicarbonate, solid line. At week 24 lactate = -0.099 ± 0.15g/kg/day, bicarbonate = 0.049 ± 0.12g/kg/day, P < 0.01, 95% confidence interval for the difference 0.068 to 0.229g/kg/day (lactate, N = 33; bicarbonate, N = 36). Kidney International 1998 54, 1731-1738DOI: (10.1046/j.1523-1755.1998.00167.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Kidney International 1998 54, 1731-1738DOI: (10. 1046/j. 1523-1755 Kidney International 1998 54, 1731-1738DOI: (10.1046/j.1523-1755.1998.00167.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Kidney International 1998 54, 1731-1738DOI: (10. 1046/j. 1523-1755 Kidney International 1998 54, 1731-1738DOI: (10.1046/j.1523-1755.1998.00167.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Kidney International 1998 54, 1731-1738DOI: (10. 1046/j. 1523-1755 Kidney International 1998 54, 1731-1738DOI: (10.1046/j.1523-1755.1998.00167.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Kidney International 1998 54, 1731-1738DOI: (10. 1046/j. 1523-1755 Kidney International 1998 54, 1731-1738DOI: (10.1046/j.1523-1755.1998.00167.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Kidney International 1998 54, 1731-1738DOI: (10. 1046/j. 1523-1755 Kidney International 1998 54, 1731-1738DOI: (10.1046/j.1523-1755.1998.00167.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Kidney International 1998 54, 1731-1738DOI: (10. 1046/j. 1523-1755 Kidney International 1998 54, 1731-1738DOI: (10.1046/j.1523-1755.1998.00167.x) Copyright © 1998 International Society of Nephrology Terms and Conditions