Breakfast Consumption Affects Appetite, Energy Intake, and the Metabolic and Endocrine Responses to Foods Consumed Later in the Day in Male Habitual Breakfast Eaters Melody Chang
Introduction Blood glucose rises following a meal, beta-cells of the pancreas release insulin and amylin appetite and food intake Fasting, beta-cells of the pancreas release glucagon, appetite and food intake Ghrelin is a peptide hormone, produced by stomach and stimulate appetite. Normally during fasting, following food intake
Purpose To compare the effects of consuming breakfast with omitting breakfast on energy intake, subjective appetite responses, and the metabolic and endocrine responses to foods consumed later in the day Hypothesis breakfast consumption will affect appetite, energy intake and metabolic and endocrine responses Purpose: aim in this study was to investigate the effects of breakfast consumption on subjective appetite, energy intake, and the response to a liquid preload.
Methods Participants: healthy weight, 12 male, regular breakfast eater Test meals - evening meal - 20:00 no other foods or drinks (other than water) - breakfast - preload - lunchtime test meal - appetite ratings (VAS) - blood sampling ( BG, insulin, FFA, GLP-1, PYY, Ghrelin)
Methods Study protocol: - Breakfast (B)/ no breakfast (NB) - fasting blood sample - VAS baseline rating of appetite - 150 min… blood sample and VAS - liquid preload - VAS ( immediately, 30 , 60, 90 min) - Blood samples collected at 15-min intervals - lunch provide - VAS ( immediately, 30, 60, 90, 120 min) cannula insert into dorsal hand vein
Results: Insulin (pmol/L) FFA (mmol/L) Glucose(mmol/L) This suggests a degree of insulin resistance in response to the liquid preload following the omission of breakfast, Prolong periods of fasting, and omitting breakfast cause a degree of insulin resistance Glucose(mmol/L)
Results GLP-1 (pmol/L) Ghrelin (pmol/L) PYY (pmol/L)
Results Subjective fullness rating Subjective hunger rating
Results Gastric emptying: rate of increase tended to be greater in B trail Energy intake: was lower in B trail
Discussion/Conclusion Missing breakfast causes metabolic and hormonal differences in the responses to foods consumed later as well as in subjective appetite and increase in energy intake.
Further Studies Recruit more population ( for example, not regular breakfast eaters, female, different regions….)