Prenatal diagnosis and management of junctional ectopic tachycardia

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Flecainide-induced incessant orthodromic atrioventricular reentrant tachycardia in Wolff- Parkinson-White syndrome: Uneven depression of accessory pathway.
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Prenatal diagnosis and management of junctional ectopic tachycardia S. Javed Zaidi, MD, Saad Siddiqui, MD, Bettina F. Cuneo, MD, Janette F. Strasburger, MD, Robert McDuffie, MD, Ronald T. Wakai, PhD  HeartRhythm Case Reports  Volume 3, Issue 11, Pages 503-508 (November 2017) DOI: 10.1016/j.hrcr.2017.07.022 Copyright © 2017 Heart Rhythm Society Terms and Conditions

Figure 1 Case 1: Fetal magnetocardiography (fMCG) recordings during and after junctional ectopic tachycardia (JET). A: MCG fetal heart rate (FHR) trend recording over 10 minutes at 20 weeks gestational age (GA) during incessant JET (181 beats per minute). Low FHR variability is seen, except during ventriculoatrial (VA) dissociation with resultant sinus capture (horizontal arrows). Periods of VA dissociation are associated with increased beat-to-beat heart rate variability and spikes in FHR owing to shortened R-R intervals from conducted beats. B: fMCG rhythm tracing at 20 weeks GA during JET. The sinus P waves are indicated by upward arrows. Retrograde P waves are indicated by downward arrows. The 2 early beats (asterisks) are preceded by a P wave and have different QRS morphology, consistent with conducted sinus capture beats. These support that antegrade atrioventricular node conduction is still present. C: Signal-averaged butterfly (20 weeks GA) showing retrograde bifid P waves occurring within the lower-amplitude T waves. QTc is prolonged. Cardiac intervals are as follows: R-R = 333 ms, VA = 77 ms, QRS = 33 ms, and QTc = 513 ms. D: Signal-averaged butterfly plot at 25 weeks GA during sinus rhythm showing tall P waves and P-R prolongation. HeartRhythm Case Reports 2017 3, 503-508DOI: (10.1016/j.hrcr.2017.07.022) Copyright © 2017 Heart Rhythm Society Terms and Conditions

Figure 2 Cases 1 and 2 postnatal electrocardiograms (ECGs) (leads II and V1). Case 1: At age < 1 day (A–C) and age 2 days (D). A: Second-degree atrioventricular (AV) block, left bundle branch block (LBBB). B: Sinus rhythm with first-degree AV block, LBBB. C: Junctional ectopic tachycardia (JET) demonstrating probable drug-related LBBB. D: Sinus rhythm; the LBBB has resolved. Case 2: At age < 1 day (E, F) and age 6 and 9 days (G, H). All ECGs are recorded at an amplitude of 0.1 mV/mm and at 25 mm/s. E: JET, 1:1 retrograde ventriculoatrial (VA) conduction. F: JET, VA dissociation possibly secondary to flecainide. G: JET with VA dissociation, the sinus capture beat in V1 suggests intact AV conduction. HeartRhythm Case Reports 2017 3, 503-508DOI: (10.1016/j.hrcr.2017.07.022) Copyright © 2017 Heart Rhythm Society Terms and Conditions

Figure 3 Case 2. Spectral Doppler images of junctional ectopic tachycardia (JET). A: Ascending aorta (Ao) and superior vena cava (SVC) waveforms. Atrial systole (seen as retrograde SVC flow velocities [arrows]) occurs simultaneously with ventricular systole (antegrade Ao flow velocity). B: A sinus capture beat (arrow) is seen from simultaneous mitral E inflow (MV) and Ao outflow. C: Increased retrograde flow during atrial systole (atrial wave [a] below baseline) is seen in the ductus venosus. Flow toward the heart is biphasic (S and D waves). HeartRhythm Case Reports 2017 3, 503-508DOI: (10.1016/j.hrcr.2017.07.022) Copyright © 2017 Heart Rhythm Society Terms and Conditions