Fig. 3 CSF1 is expressed in human melanoma.

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Fig. 1 CSF1 is increased in blood of melanoma patients and correlates with disease progression. CSF1 is increased in blood of melanoma patients and correlates.

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Fig. 3 CSF1 is expressed in human melanoma. CSF1 is expressed in human melanoma. (A) Representative multiplexed fluorescence staining images of tumor tissue from one melanoma patient (LAU1283) stained with 4′,6-diamidino-2-phenylindole (DAPI) (blue) and antibodies against S100 (green) or CSF1 (red). The red square in the upper panel indicates a region of interest that has been magnified in the lower panels. Scale bar, 100 μm. (B) Percentage of S100+ melanoma cells that are also CSF1+ in primary melanomas (n = 4) and melanoma metastases (n = 4) from the patients listed in table S1. Each data point represents the average (means ± SEM) of three to five images per tumor area for each patient. S1 to S3 indicate three individual specimens from patient LAU1283 (details are provided in table S1). Natalie J. Neubert et al., Sci Transl Med 2018;10:eaan3311 Published by AAAS