I. G. Otterness, Ph. D. , M. -P. H. Le Graverand, M. D. , Ph. D. , F

Slides:



Advertisements
Similar presentations
Efficacy of ultrasound therapy for the management of knee osteoarthritis: a systematic review with meta-analysis A. Loyola-Sánchez, J. Richardson, N.J.
Advertisements

The relationship between specific tissue lesions and pain severity in persons with knee osteoarthritis Ms L. Torres, B.A., Dr D.D. Dunlop, Ph.D., Dr C.
The association between metacarpal ratio, radiographic hand and knee osteoarthritis and its progression after meniscectomy  P.T. Paradowski, L.S. Lohmander,
Lateral and medial joint space narrowing predict subsequent cartilage loss in the narrowed, but not in the non-narrowed femorotibial compartment – data.
Two year longitudinal change and test–retest-precision of knee cartilage morphology in a pilot study for the osteoarthritis initiative  F. Eckstein, M.D.,
The relationships between bone mineral density in the spine, hip, distal femur and proximal tibia and medial minimum joint space width in the knees of.
Dr L. S. Kim, N. D. , Dr L. J. Axelrod, N. D. , Dr P. Howard, M. D
H.J. Smith, Ph.D., J.B. Richardson, M.D., A. Tennant, Ph.D. 
The epidemiology and impact of pain in osteoarthritis
P.-S. Hsu, H.-H. Lin, C.-R. Li, W.-S. Chung 
Disability and quality of life of patients with knee or hip osteoarthritis in the primary care setting and factors associated with general practitioners'
Osteoarthritis as a disease of mechanics
The acutely ACL injured knee assessed by MRI: changes in joint fluid, bone marrow lesions, and cartilage during the first year  R.B. Frobell, P.T., Ph.D.,
Association of knee pain with a reduction in thigh muscle strength – a cross-sectional analysis including 4553 osteoarthritis initiative participants 
J. Duryea, Ph. D. , G. Neumann, M. D. , M. H. Brem, M. D. , W. Koh, M
Women have thinner cartilage and smaller joint surfaces than men after adjustment for body height and weight  I.G. Otterness, Ph.D., F. Eckstein, M.D. 
Osteoarthritis year 2011 in review: biochemical markers of osteoarthritis: an overview of research and initiatives  Y. Henrotin  Osteoarthritis and Cartilage 
Predictive and concurrent validity of cartilage thickness change as a marker of knee osteoarthritis progression: data from the Osteoarthritis Initiative 
A new non-invasive method to assess synovitis severity in relation to symptoms and cartilage volume loss in knee osteoarthritis patients using MRI  J.-P.
Lateral and medial joint space narrowing predict subsequent cartilage loss in the narrowed, but not in the non-narrowed femorotibial compartment – data.
K. Zou, M.D., G. Liu, M.D., T. Wu, M.D., L. Du, M.D. 
Changes in biochemical markers and prediction of effectiveness of intra-articular hyaluronan in patients with knee osteoarthritis  M. Hasegawa, M.D.,
C-reactive protein, metabolic syndrome and incidence of severe hip and knee osteoarthritis. A population-based cohort study  G. Engström, M.D., Ph.D.,
Health-related quality of life and costs in patients with osteoarthritis on waiting list for total knee replacement  M. Núñez, Ph.D., E. Núñez, Ph.D.,
Incidence of symptomatic osteochondritis dissecans lesions of the knee: a population- based study in Olmsted County  A. Pareek, T.L. Sanders, I.T. Wu,
Efficacy and safety of intraarticular hyaluronic acid in the treatment of hip osteoarthritis: a systematic review  J.C. Fernández López, M.D., Ph.D.,
Brace treatment for osteoarthritis of the knee: a prospective randomized multi-centre trial  R.W. Brouwer, M.D., T.M. van Raaij, M.D., J.A.N. Verhaar,
Comparison of load responsiveness of cartilage T1rho and T2 in porcine knee joints: an experimental loading MRI study  H. Hamada, T. Nishii, S. Tamura,
Time to be positive about negative data?
Equivalence of a single dose (1200 mg) compared to a three-time a day dose (400 mg) of chondroitin 4&6 sulfate in patients with knee osteoarthritis. Results.
Knee cartilage assessment with MRI (dGEMRIC) and subjective knee function in ACL injured copers: a cohort study with a 20 year follow-up  P. Neuman, H.
J. Avouac, M.D., L. Gossec, M.D., M. Dougados, M.D. 
Structural adaptations in compressed articular cartilage measured by diffusion tensor imaging  S.K. de Visser, B.Eng. (Med.), R.W. Crawford, D.Phil.,
S. Sonne-Holm, M.D., Dr. Sci., S. Jacobsen, M.D. 
N.D. Miljkovic, M.D., Ph.D., G.M. Cooper, Ph.D., K.G. Marra, Ph.D. 
Risk factors associated with reduced work productivity among people with chronic knee pain  M. Agaliotis, M. Fransen, L. Bridgett, L. Nairn, M. Votrubec,
Low rate of total hip replacement as reflected by a low prevalence of hip osteoarthritis in South Korea  H.A. Kim, M.D., Ph.D., S.H. Koh, M.D., Ph.D.,
Association between body mass index and risk of total knee replacement, the Singapore Chinese Health Study  Y.-Y. Leung, J.C. Allen, M. Noviani, L.-W.
Effectiveness of thermal and athermal short-wave diathermy for the management of knee osteoarthritis: a systematic review and meta-analysis  Y. Laufer,
Assessment of joint space narrowing with conventional standing antero-posterior radiographs: relief in mild-to-moderate pain is not a confounder in recent.
Medial arch supports do not significantly alter the knee adduction moment in people with knee osteoarthritis  R.S. Hinman, L. Bardin, M. Simic, K.L. Bennell 
Clinically important body weight gain following total hip arthroplasty: a cohort study with 5-year follow-up  D.L. Riddle, J.A. Singh, W.S. Harmsen, C.D.
Rates and sensitivity of knee cartilage thickness loss in specific central reading radiographic strata from the osteoarthritis initiative  S. Maschek,
Utilization rates of hip arthroplasty in OECD countries
M.D. Westby, D.A. Marshall, C.A. Jones  Osteoarthritis and Cartilage 
Risk factors for onset of osteoarthritis of the knee in older adults: a systematic review and meta-analysis  M. Blagojevic, C. Jinks, A. Jeffery, K.P.
A graphic user interface for the evaluation of knee osteoarthritis (GEKO): an open- source tool for histological grading  H.E. Kloefkorn, B.Y. Jacobs,
Who should have a joint replacement? A plea for more ‘phronesis’
Volumetric bone mineral density of the tibia is not increased in subjects with radiographic knee osteoarthritis  M. Abdin-Mohamed, M.B.B.S., M.R.C.P.,
Validation of a self-report instrument for assessment of hallux valgus
D.J. Hunter  Osteoarthritis and Cartilage 
A comparison of intra-articular hyaluronan injection accuracy rates between three approaches based on radiographic severity of knee osteoarthritis  Y.
S.G. Muthuri, D.F. McWilliams, M. Doherty, W. Zhang 
Most patients gain weight in the 2 years after total knee arthroplasty: comparison to a healthy control group  J.A. Zeni, L. Snyder-Mackler  Osteoarthritis.
Body mass index and alignment and their interaction as risk factors for progression of knees with radiographic signs of osteoarthritis  E. Yusuf, J. Bijsterbosch,
C. Ratzlaff, M. Koehoorn, J. Cibere, J. Kopec 
T. Silvestri, M. D. , L. Pulsatelli, Ph. D. , P. Dolzani, Ph. D. , A
Falls risk is associated with pain and dysfunction but not radiographic osteoarthritis in older adults: Tasmanian Older Adult Cohort study  S.J. Foley,
Development and preliminary evaluation of the OsteoArthritis Questionnaire (OA- Quest): a psychometric study  L. Busija, R. Buchbinder, R.H. Osborne  Osteoarthritis.
Osteoarthritis year 2012 in review: biology
Knee cartilage defects: association with early radiographic osteoarthritis, decreased cartilage volume, increased joint surface area and type II collagen.
Investigations in generalized osteoarthritis
R. B. Souza, C. Stehling, B. T. Wyman, M. -P. Hellio Le Graverand, X
Systematic review of the impact of osteoarthritis on health outcomes for comorbid disease in older people  L. Parkinson, D.L. Waters, L. Franck  Osteoarthritis.
Osteoarthritis year in review 2016: mechanics
Examining a whole-organ magnetic resonance imaging scoring system for osteoarthritis of the knee using Rasch analysis  P.G. Conaghan, M.B.B.S., Ph.D.,
The relationship between foot and ankle symptoms and risk of developing knee osteoarthritis: data from the osteoarthritis initiative  K.L. Paterson, J.
Changes in pain, stiffness and physical function in patients with osteoarthritis waiting for hip or knee joint replacement surgery  H. Kapstad, R.N.,
M. Doherty, P. Dieppe  Osteoarthritis and Cartilage 
General Information Osteoarthritis and Cartilage
Presentation transcript:

Allometric relationships between knee cartilage volume, thickness, surface area and body dimensions  I.G. Otterness, Ph.D., M.-P.H. Le Graverand, M.D., Ph.D., F. Eckstein, M.D., Med.  Osteoarthritis and Cartilage  Volume 16, Issue 1, Pages 34-40 (January 2008) DOI: 10.1016/j.joca.2007.05.010 Copyright © 2007 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 Correlation of the VC of the knee with the tAB of the knee. The data were fit to the equation VC=a×tAB1.5 where a=0.0256, r2=0.86 and P<0.00001. () Females, (●) Males. Osteoarthritis and Cartilage 2008 16, 34-40DOI: (10.1016/j.joca.2007.05.010) Copyright © 2007 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 The relationship of the tAB with height squared. (A) The least squares fit tAB=a×height2 applied to females and males together (a=0.0028, r2=0.67, P<0.0001). (B) The least squares fit b×sex+a×height2 where sex=0 or 1 for females or males, respectively (a=0.0028, b=9.54, r2=0.76, P<0.0001). (C) The least square fit for tAB=a×height2 with females only (a=0.0028, r2=0.60, P<0.0001). (D) The least squares fit for tAB=a×height2 with males only (a=0.0037, r2=0.16, P<0.01). () Females, (●) Males. Osteoarthritis and Cartilage 2008 16, 34-40DOI: (10.1016/j.joca.2007.05.010) Copyright © 2007 Osteoarthritis Research Society International Terms and Conditions

Fig. 3 The relation of the VC for the total knee (K) with height cubed. (A) The least squares fit VC=a×height3 applied to females and males together (a=4.17×10−6, r2=0.54, P<0.0001). (B) The least squares fit VC=b×sex+a×height3 where sex=0 or 1 for females or males, respectively (a=3.69×10−6, b=4.38, r2=0.65, P<0.0001). (C) The least square fit for VC=a×height3 with females only (a=3.70×10−6, r2=0.38, P<0.0001). (D) The least squares fit for VC=a×height3 with males only (a=4.40×10−6, r2=0.09, P=0.03). () Females, (●) Males. Osteoarthritis and Cartilage 2008 16, 34-40DOI: (10.1016/j.joca.2007.05.010) Copyright © 2007 Osteoarthritis Research Society International Terms and Conditions