DNA History & Structure AP Biology DNA History & Structure
Nucleic Acid Structure
Complimentary Base Pairing
Frederick Griffith
Frederick Griffith Experiment Mixture of heat-killed S cells and living R cells Living S cells (control) Living R cells (control) Heat-killed S cells (control) RESULTS Mouse dies Mouse healthy Mouse healthy Mouse dies Living S cells are found in blood sample
Oswald Avery
Alfred Hershey & Martha Chase
Bacteriaphage injecting it’s DNA into a bacterial cell
Electron Microscope View
Hershey – Chase Experiment
Erwin Chargaff
Adenine = Thymine (DNA) or Uracil (RNA) Chargaff’s Rule Adenine = Thymine (DNA) or Uracil (RNA) & Guanine = Cytosine If you know the % composition of 1, you can find the % composition of the other 3.
Rosalind Franklin
DNA from a top view
DNA from a side view
James Watson & Francis Crick with their DNA model
See the HYDROGEN bonds?