Amphetamine Modulates Human Incentive Processing

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Amphetamine Modulates Human Incentive Processing Brian Knutson, James M Bjork, Grace W Fong, Daniel Hommer, Venkata S Mattay, Daniel R Weinberger  Neuron  Volume 43, Issue 2, Pages 261-269 (July 2004) DOI: 10.1016/j.neuron.2004.06.030

Figure 1 Positive Arousal by Drug Treatment Effects of AMPH versus PLAC treatment on positive arousal (*p < .05). Neuron 2004 43, 261-269DOI: (10.1016/j.neuron.2004.06.030)

Figure 2 Right NAcc Peak Anticipatory Activation and Correlations with Positive Arousal Right NAcc peak activation during incentive anticipation by condition and drug treatment and plotted versus excitement (mean-deviated) across all cue conditions and subjects (lag = 6 s, *p < .05, AMPH versus PLAC). Neuron 2004 43, 261-269DOI: (10.1016/j.neuron.2004.06.030)

Figure 3 Right MPFC Peak Outcome Activation Right MPFC peak activation in response to hit and miss outcomes by condition and drug treatment (lag = 6 s). Neuron 2004 43, 261-269DOI: (10.1016/j.neuron.2004.06.030)

Figure 4 Gain versus Nongain Activation Maps and Right NAcc Time Courses by Drug Treatment Effects of AMPH versus PLAC treatment on gain versus nongain anticipation contrast maps and right NAcc activation time courses (n = 8, within-subjects). Abbreviations: ant, anticipation; rsp, response; out, outcome. *p < .05 +$5.00 versus +$0.00. Neuron 2004 43, 261-269DOI: (10.1016/j.neuron.2004.06.030)