ANATOMY Unit 3 Notes: Sliding Filament Theory

Slides:

Advertisements

Similar presentations

Muscle Contraction.

Advertisements

Skeletal Muscle Activity: Contraction

Neuromuscular Junction

Depolarization Initially, this is a local electrical event called end plate potential Later, it ignites an action potential that spreads in all directions.

Destruction of Acetylcholine

Muscles and Muscle Tissue

Molecular Basis of Skeletal Muscle Contraction Dr. Abdelrahman Mustafa Department of Basic Medical Sciences Division of Physiology Faculty of Medicine.

Notes: Sliding Filament Theory [Muscle Contraction Physiology]

The Sliding Filament Theory. Steps to the Sliding Filament Theory 1.A message originates in the brain and is released to the central nervous system (CNS)

Contraction of Skeletal Muscle Sliding filament theory of contraction (Excitation-Contraction Coupling)

Muscles n Skeletal muscle organization and how it contracts.

Muscular system SKELETAL MUSCLE Skeletal muscle is made up of hundreds of muscle fibers –Fibers consists of threadlike myofibrils –Myofibrils composed.

Sliding Filament Theory Review

Histology of Muscle.

09_10 Sliding filament theory Slide number: 1 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Tropomyosin.

Skeletal Muscle Key words:. Overview of the Muscle Fiber Structure Muscle fibers (cells) are composed of myofibrils Myofibrils are composed of myofilaments.

Muscle Contraction Tendon – cord of dense fibrous tissue attaching the muscle to a bone. Epimysium – the sheath of fibrous connective tissues surrounding.

MUSCLE CONTRACTION. Microscopic Anatomy of Skeletal Muscle Sarcomere Contractile unit of a muscle fiber Figure 6.3b.

Muscle Contraction. Muscle Movement Muscle fiber must be stimulated: – By an electrical signal called muscle action potential (AP) – Delivered by motor.

Muscle Cells & Muscle Fiber Contractions

Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Muscle Contraction.

Chapter 9 Muscular System Part II.

Pages  Stimulus generated capabilities: ◦ Irritability (also called responsiveness)—ability to receive and respond to a stimulus ◦ Contractility—ability.

Contraction of skeletal muscles. Energy Needed for Contraction 1. Aerobic Respiration (oxidative phosphorylation) Majority of ATP comes from this process.

40 pt 60 pt 80 pt 100 pt 20 pt 40 pt 60 pt 80 pt 100 pt 20 pt 40 pt 60 pt 80 pt 100 pt 20 pt 40 pt 60 pt 80 pt 100 pt 20 pt 40 pt 60 pt 80 pt 100 pt 20.

Question 1 Explain the primary differences between smooth, skeletal, and cardiac muscle tissue Skeletal muscle fibers are cylindrical, multinucleate cells,

Sensory and Motor Mechanisms – chpt 49-. I. Anatomy & physiology of Muscular system n A. 3 types of muscle tissue –1. skeletal muscle aka striated muscle–

Ch : Contraction and Metabolism of Skeletal Muscle

Sliding Filament.

Filaments Resting state Electrical impulse (Action Potential) reaches axon terminal.

Synapse – The site of connection between a neuron and a cell. Neurotransmitter – A chemical released at the neuron’s synapse that communicates with the.

Muscle Physiology Dynamics of Muscle Contraction MMHS Anatomy.

The Physiology of Skeletal Muscle Contraction

Neuromuscular Junction and Major Events of Muscle Contraction Quiz Review.

Lecture #21 Date ____ n Chapter 49 ~ Sensory and Motor Mechanisms.

The Neuromuscular Junction or end plate - the point where the effector nerve meets a skeletal muscle - many end plates spread throughout a muscle to.

Muscle Contraction. 1.Acetylcholine (Ach) is released from the axon terminal (nerve) into the synaptic cleft and binds to Ach receptors in the sarcolemma.

Neuron Function The Membrane Potential – Resting potential Excess negative charge inside the neuron Created and maintained by Na-K ion pump Copyright ©

Muscle Contraction.

Muscles and Muscle Tissue P A R T B. Depolarization Initially, this is a local electrical event called end plate potential Later, it ignites an action.

Muscle System. Root Words 3 Kinds of Muscle Skeletal Smooth (stomach, intestine) Cardiac.

Muscle Contraction Chapter 9 Part B. How does the anatomical structure function physiologically? What is the importance of the membranes? Why is it important.

Skeletal Muscle Blank.

Muscles and Muscle Tissue

The Muscular System What do skeletal muscles do? How do muscles work?

Muscle contraction.

2. Striation Pattern of Sarcomere

Initially Sarcolemma is in the Resting Membrane state

9 Muscles and Muscle Tissue: Part B-Muscle Contraction and Signal Transmission.

Nerve MUSCLE PHYSIOLOGY

How does the muscle get the message?

9 Muscles and Muscle Tissue: Part B.

The Muscular System What do skeletal muscles do? How do muscles work?

Introductory Skeletal Muscle – Histology Flash Cards

Physiology of Muscle Contraction

NOTES: The Muscular System (Ch 8, part 2)

Shortening of sarcomeres = muscle shortening

Physiology Review The SARCOMERE is the functional unit of the muscle.

NOTES: The Muscular System (Ch 8, part 3)

Microanatomy of Muscles

Excitation-Contraction Coupling 1. Impulse arrives from motor neuron 2. Neuron releases acetylcholine (Ach) into synapse with muscle 3.

Gnarly Nervous Physiology

MUSLCES PART 2 HOW DO THEY WORK?.

Unit 2 Notes: Muscles & Contractions

Physiology of Muscle Contraction

Sliding Filament Theory

Contraction of Skeletal Muscle

Presentation transcript:

ANATOMY Unit 3 Notes: Sliding Filament Theory

(1) Muscle Contraction Sliding Filaments = Muscle Contraction The Basic Steps: 1- Message sent 2- Neurotransmitter 3- Depolarization 4- Calcium + Troponin = Actin Exposed 5- Actin + Myosin (Contraction)

(2) Neuron to Muscle Cause: Conscious decision to move Homeostatic response Nervous System Sends a Message to the Effector Organ: Neurotransmitter released (ACh, acetylcholine) ACh binds to sarcolemma of muscle fiber ACh initiates opening of sodium-potassium channels

(3) Depolarization of the Muscle Cause: Binding of ACh to sodium-potassium channels Opening of channels + Movement of Na-K+ across sarcolemma Involves the Movement of Charges: More Na+ moves in, Than K+ moves out Imbalance of charges  electrical current (action potential)

(4) The Release of Calcium Cause: Depolarization Action Potential across the Sarcoplasmic Reticulum causes the release of Calcium: Ca+ released from membrane of sarcoplasmic reticulum. Ca+ binds with troponin: Troponin-Tropomyosion conformation changes Troponin & Tropomyosin no longer cover Actin Actin is exposed

(5) Myosin interacts with Actin: Cause: Troponin & Tropomyosin unveils Actin Actin exposed Myosin releases Inorganic Phosphate + ADP Pi + ADP = ATP Myosin changes conformation Myosin binds to Actin Myosin and Actin slide towards each other WE HAVE A CONTRACTION! WOO WOO!

(6) Relaxation ATP binds back with myosin… Myosin detaches and moves away from Actin Troponin & Tropomyosin cover up Actin Ca+ moves back into Sarcoplasmic Reticulum Repolarization  Sarcolemma stable again

(7) Why is it called the Sliding Filament Theory? Movement of myofilaments causes contraction Myosin grabs actin & SLIDES them towards the center

(1-2) Depolarization of Sarcolemma & Generation of Action Potential (3) Calcium Ions released from Sarcoplasmic Reticulum (10) Everything moves back & contraction done! (4-6) Calcium binds to troponin, tropomyosin moves, actin exposed (9) Calcium removed by active transport (7-8) Myosin attaches to actin, Myosin moves actin, ATP released