Effect of semen quality on human sex ratio in in vitro fertilization and intracytoplasmic sperm injection: an analysis of 27,158 singleton infants born after fresh single-embryo transfer Mikiko Arikawa, M.D., Seung Chik Jwa, M.D., Ph.D., M.P.H., Akira Kuwahara, M.D., Ph.D., Minoru Irahara, M.D., Ph.D., Hidekazu Saito, M.D., Ph.D. Fertility and Sterility Volume 105, Issue 4, Pages 897-904 (April 2016) DOI: 10.1016/j.fertnstert.2015.12.009 Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions
Figure 1 Second sex ratio (SSR) and 95% confidence intervals stratified by fertilization method and embryo stage at transfer. Blastocyst embryo transfer demonstrates a statistically significantly higher SSR in in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI). There was no statistically significant interaction between blastocyst embryo transfer and fertilization method (P=.55 for interaction), suggesting that the effect of blastocyst embryo transfer is similar in both IVF and ICSI. Fertility and Sterility 2016 105, 897-904DOI: (10.1016/j.fertnstert.2015.12.009) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions