William J. Welch, Christopher S. Wilcox Kidney International

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AT1 receptor antagonist combats oxidative stress and restores nitric oxide signaling in the SHR William J. Welch, Christopher S. Wilcox Kidney International Volume 59, Issue 4, Pages 1257-1263 (April 2001) DOI: 10.1046/j.1523-1755.2001.0590041257.x Copyright © 2001 International Society of Nephrology Terms and Conditions

Figure 1 Mean ± SEM values for absolute increases in maximal tubuloglomerular feedback (TGF) responses during luminal perfusion with artifical tubular fluid (ATF) + 7-nitroindazole (7-NI; 10-4 mol/L) compared with ATF + vehicle. Data are compared in nephrons studied without (□; A or ▪; B) or during (?) microperfusion of tempol (10-4 mol/L) in artificial plasma (AP) into the efferent arteriole (EA). Groups of WKY rats (A) or SHRs (B) were administered with vehicle (Veh), hydralazine + hydrochlorothiazide + reserpine (HHR), or candesartan (Cand) for two weeks prior to testing. Kidney International 2001 59, 1257-1263DOI: (10.1046/j.1523-1755.2001.0590041257.x) Copyright © 2001 International Society of Nephrology Terms and Conditions