Mutations The fat cat sad.

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Mutations The fat cat sad

Point Mutation ONLY 1 Base is either INSERTED or DELETED from the mRNA sequence. ORIGINAL 5’ – AGGUAACAUUCC – 3’ INSERTION 5’ – AGGUAAACAUUCC – 3’ DELETION

Frameshift Mutation POINT mutations lead to FRAMESHIFT mutations. The READING frame shifts or moves to a different set of 3 bases (CODON) 5’ – AGGUAACAUUCC – 3’ 5’ – AGGUAAACAUUCC – 3’

Frameshift Mutation Cont. Frameshifts are when there is an INSERTION or DELETION of bases that are NOT DIVISABLE by 3. ORIGINAL: 5’ – AGGUAACAUUCC – 3’ If I insert 2 bases, do I have a frame shift? 5’ – AGGUCAAACAUUCC – 3’ If I delete 6 bases, do I have a frame shift? 5’ – AGGUAACAUUCC – 3’

Mutagens cause Mutations A substance (chemical or physical), exposure to which increases the likelihood of mutation. Examples?