Old friends form alliance against podocytes

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Old friends form alliance against podocytes Matias Simons, Tobias B. Huber Kidney International Volume 80, Issue 11, Pages 1117-1119 (December 2011) DOI: 10.1038/ki.2011.298 Copyright © 2011 International Society of Nephrology Terms and Conditions

Figure 1 TGF-β1-mediated activation of Wnt signaling leads to podocyte stress and injury. One hypothetical reason for reactivation of this developmental pathway could be the stimulation of progenitor cells for glomerular regeneration. A similar balance between podocyte death and repair has recently been shown for the Notch pathway. Kidney International 2011 80, 1117-1119DOI: (10.1038/ki.2011.298) Copyright © 2011 International Society of Nephrology Terms and Conditions