Crossover Therapies The Research Cycle

Ivermectin Heartgard + used to prevent heartworms in dogs https://www.youtube.com/watch?v=Eo_-DQY4ODM Merck & Co 1981 introduced as Ivomec to treat lung worms and other nematode parasites of cattle

Onchocerciasis (River blindness) Found in Africa and South America Threatens more than 100 million people with blindness Transmitted by African black fly Nematode=Onchocerca volvulus worms burrow under skin and can live 10-15 years and grow up to 2 feet

Onchocerciasis (River blindness) when reproducing the worms release millions of microfilariae into the blood and some migrate and invade the eye http://www.animalplanet.com/tv-shows/monsters-inside-me/videos/river-blindness.htm

Onchocerciasis (River blindness) Mectizan (Ivermectin) kills the microfilariae Ivermectin is the first pharmaceutical created for dogs that has been adapted for humans

Mectizan (Ivermectin) Also used to treat scabies in humans

CDC Info http://wwwnc.cdc.gov/travel/yellowbook/2014/chapter-3-infectious-diseases-related-to-travel/onchocerciasis-river-blindness