Towards personalized health care in OA

Slides:

Advertisements

Similar presentations

Effects of exercise and weight loss on interstitial matrix turnover and tissue inflammation biomarkers in adults with knee osteoarthritis: the intensive.

Advertisements

Full-thickness cartilage defects repaired by human induced pluripotent stem cells (IPSCS)-derived mesenchymal stem cells and plga scaffolds D. Shi, X.

P.-S. Hsu, H.-H. Lin, C.-R. Li, W.-S. Chung

A. Bhave, M. Mont, M. Chugthai, R. Starr Osteoarthritis and Cartilage

R. Takeuchi, H. Ishikawa, T. Kuniya, A. Nakazawa

S. Gavard Osteoarthritis and Cartilage

Role of endothelin-1 in endochondral ossification and osteoarthritis

Automatic cartilage segmentation and measurement for diagnosis of OA using 3D box and Gaussian filters X. Cui, S. Li, M. Yu, H. Kim, K.-S. Kwack, B.-H.

Effect of self assembled peptide-mesenchymal stem cell complex on delaying the progression of osteoarthritis S. Kim, S. Lee, Y. Jung, J. Kim, S. Kim

Comparison of the Usefulness of Laser-induced Photoacoustic Measurement & Magnetic Resonance Imaging (T2 Mapping, Diffusion Tensor Imaging) for Assessing.

Chondrocyte pro-proliferative compounds may utilize extracellular matrix remodeling processes to regenerate cartilage D. Reker, C. Kjelgaard-Petersen,

Damage to The Extracellular Matrix (ECM) in Articular Cartilage is Observed via Changes in The T2–T2 Exchange Rates Between Fluid in The Pore Space and.

The effect of conditional macrophage depletion on development of injury-induced knee OA in obese transgenic MAFIA mice C.-L. Wu, J. McNeill, K. Goon,

P. Yuan, X. Zhang, W. Yang, W. Kang, B. Yang, J. li, B. Chen, X. Li, B

Efficacy of the selective inducible nitric oxide synthase inhibitor sd-6010 in nonclinical inflammatory, neuropathic, and osteoarthritis pain J.R. Connor,

The approach consortium: a 2-year, European, cohort study to describe, validate, and predict phenotypes of knee osteoarthritis by use of clinical, imaging,

R. Nakamura, N. Komatsu, K. Fujita, H. Nishimura, Y. Katsuki

B. Vafaeian, S. Adeeb, M. El-Rich, J. Jaremko

Assessing the characteristics of human mesenchymal stromal cells derived from bone marrow and umbilical cord following expansion in the quantum® hollow-fibre.

The combined efficacy of multimodal non-surgical treatment on pain and sensitization in patients with knee osteoarthritis not eligible for a total knee.

Two different knee braces alter patella position: a moving image analysis using weight bearing magnetic resonance imaging M.J. Callaghan, N.D. Reeves,

The influence of early osteoarthritic collagen network de-structuring in articular cartilage on the tissue stiffness and swelling properties M. Nickien,

Mice with global deletion of mitogen inducible gene 6 display rapid and severe cartilage and subchondral bone damage after ligament and meniscus injury

Y. Levy, A. Hasegawa, S. Patil, M. Lotz, D. D'Lima

Effect of soft braces on pain and physical function in patients with knee osteoarthritis: systematic review with meta-analyses T. Cudejko, M. van der.

Coordinate and synergistic effects of extensive treadmill exercise and ovariectomy on articular cartilage degeneration K. Miyatake, K. Tsuji, J. Yamada,

C. -H. Chou, H. -G. Wisniewski, P. Band, J. Huebner, T. Stabler, C

Different distribution and activation degree of th17 cells in peripheral blood in patients with osteoarthritis, rheumatoid arthritis and healthy donors:

Optimizing methods to generate tissue engineered cartilage constructs under serum free conditions in suspension culture L.M. Allen, D. Ponjevic, J. Matyas,

Effects of low level laser therapy: a study of status of cartilage, subchondral bone and gait adaptation in the rat anterior cruciate ligament transection.

Structural Damage of the Thumb Base in Patients With Hand Osteoarthritis, Assessment by Magnetic Resonance Imaging Compared to Standard Radiography S.

Patients with abnormal limb kinetics at six months after anterior cruciate ligament reconstruction have a potential risk for medical meniscus abnormality.

Comparing clinical outcomes of exercise intervetions according to the American college of sports medicine guidelines for strength training to other types.

Immediate effects of a varus unloader brace on lateral knee osteoarthritis after anterior cruciate ligament reconstruction during stair ascent and stair.

Early intervention to prevent cartilage degeneration by administration of anti-vegf antibody in rabbit model T. Nagai, M. Sato, T. Kutsuna, T. Ukai,

G. van den Akker, T. Welting, D. Surtel, A. Cremers, W. Voncken, L

Z. Huang, T. Stabler, F. Pei, V. Kraus Osteoarthritis and Cartilage

Identification and characterisation of osteoarthritis patients with inflammation derived tissue turnover A.S. Siebuhr, K.K. Petersen, L. Arendt-Nielsen,

Acute influences of draw-in maneuver for knee adduction moment and hip and trunk muscle activities during a person's manner of walking S. Ota, H. Ohko,

Increased susceptibility to IL-1 accelerates osteoarthritic change in 3D-cultured chondrocytes and in vivo animal models Y. Takeda, Y. Niki, Y. Fukuhara,

Damps provide a link between joint tissue damage and pain through direct activation of TLR4 expressed by sensory neurons R.E. Miller, P.B. Tran, S. Ishihara,

S. Allaith, P. D. Clegg, E. G. Canty-Laird, S. Tew, B. Caterson, E

Total knee replacement followed by a non-surgical treatment program reduce localized and spreading pain sensitization – A pre-defined ancillary analysis.

Evidence for bone mineral density and bone resorption in middle and elderly women with knee osteoarthritis in Shanghai: a cross sectional study Q. Xiaofeng

Walking with increased foot progression angle can reduce joint compression in individuals with knee OA K. Manal, T.S. Buchanan Osteoarthritis and Cartilage

Monocyte chemoattractant protein 1 induced chondrocytes degeneration and cartilage degradation in osteoarthritis X. yuankun, K. Yan, W. Bin, L. Jian-Hao

Osteoarthritis and Cartilage

Effects of exercise and weight loss on interstitial matrix turnover and tissue inflammation biomarkers in adults with knee osteoarthritis: the intensive.

Multivariate pattern analysis of physical activity and cartilage health: data from the osteoarthritis initiative E. Halilaj, T.J. Hastie, G.E. Gold,

R. O. Peterson, S. R. Hoy, L. M. Vucetich, J. A. Vucetich, V. B

Location-specific hip joint space width for progression of hip osteoarthritis: predictive validity and responsiveness of a new computerized measure C.

Imaging biomarker with T1 and T2 mappings in osteoarthritis – In vivo human articular cartilage study C. Yan, C. Wong, T. Li, N. Gong, Q. Chan, K. Chiu

Weather, air pollution and rheumatic diseases: a prospective and correlational study of influence of weather and air pollution on the perception of joint.

Osteoarthritis year 2012 in review: biology

No treatment effects of oral glucosamine for subgroups of knee and hip osteoarthritis patients; an individual patient data meta-analysis from the OA trial.

The effect of quadriceps-strengthening exercise on quadriceps and knee biomichanics during walking in adults with knee osteoarthritis: a randomized controlled.

Diclofenac not more effective than acetaminophen in patients with mild knee osteoarthritis: results of a randomized controlled trial in primary care with.

CD14 deficiency dampens osteoclastogenesis and alters bone remodeling in a murine model of osteoarthritis C. Zhou, V. Nguyen, R. Smalley, N. Sambamurthy,

Knee kinematic and kinetic modifications under body weight unloading during overground walking at a constant speed A.G. Fischer, E.M. Debbi, A. Wolf

Adhesive barrier/directional controlled release for cartilage repair by endogenous progenitor cell recruitment G.-I. Im, J.-M. Lee, E.-A. Kim Osteoarthritis.

Biomechanical knee cartilage analysis in young professional soccer players by a T2 mapping unloading algorithm G.H. Welsch, L. Waldenmeier, C. Evers,

Quadriceps/Hamstrings co-activation during gait in individuals with anterior cruciate ligament reconstruction T. Blackburn, B. Pietrosimone, J. Goodwin,

E. M. Debbi, B. Bernfeld, E. Gray, M. Salai, Y. Levy, A. Gold, R

E. M. Debbi, B. Bernfeld, M. Falah, A. Greental, A. Sigal, R. Debi, A

Hypertrophy and structural alterations in tibiofemoral articular cartilage 6-24 months after anterior cruciate ligament reconstruction E. Thorhauer,

M. Fujii, T. Furumatsu, H. Xue, S. Miyazawa, Y. Kodama, T. Hino, Y

Intra-articular delivery of kartogenin-conjugated chitosan nano/microparticles for cartilage regeneration G.-I. Im, M. Kang, J.-Y. Ko, J. Kim Osteoarthritis.

A. Carlson, B. Bothner, R. June Osteoarthritis and Cartilage

General Information Osteoarthritis and Cartilage

Long-term effects of vitamin d supplementation and maintaining vitamin d sufficiency on knee osteoarthritis over 5 years B. Antony, S. Zheng, J. Burgess,

Presentation transcript:

Towards personalized health care in OA Towards personalized health care in OA? identification of osteoarthritis (OA) patients into four phenotypic classes depending on their level of cartilage degradation and connective tissue inflammation A-C. Bay-Jensen, A. Siebuhr, L. Lindhardt Egsgaard, O. Simonsen, T. Eskehave, L. Arendt-Nilesen, K. Kjaer Petersen, H. Hoegh, M. Karsdal Osteoarthritis and Cartilage Volume 22, Pages S72-S73 (April 2014) DOI: 10.1016/j.joca.2014.02.148 Copyright © 2014 Terms and Conditions

Osteoarthritis and Cartilage 2014 22, S72-S73DOI: (10. 1016/j. joca Copyright © 2014 Terms and Conditions