Osteoarthritis and Cartilage

Slides:

Advertisements

Similar presentations

L. J. Sandell, Ph. D. , X. Xing, M. D. , C. Franz, M. A. , S

Advertisements

M. Akagi, M. D. , Ph. D. , A. Ueda, M. D. , T. Teramura, Ph. D. , S

S. Gavard Osteoarthritis and Cartilage

Gene expression profiling for confirmation of effects of DNA polymeric molecules on in vitro arthritis model H.-J. Kim, A. Baek, M. Kim, S.-R. Cho Osteoarthritis.

In vitro cell surface markers are insufficient to identify in vivo/in situ multipotent synovial mesenchymal stem cells isolated from normal or osteoarthritic.

Prospective economic evaluation of the costs for medications and nutraceuticals in knee osteoarthritis M. Chung, N. Zhao, J.B. Wong, C. Wang Osteoarthritis.

Decreased proteoglycan degradation in IL-1β-treated cartilage co-cultured with TIMP-3- transduced cells J. Mason, A. Donahue, A. Yoskowitz, D. Richardson

Role of endothelin-1 in endochondral ossification and osteoarthritis

Mineralization of meniscal enthesis in osteoarthritic knees

Effect of self assembled peptide-mesenchymal stem cell complex on delaying the progression of osteoarthritis S. Kim, S. Lee, Y. Jung, J. Kim, S. Kim

Effect of mechanical stress on the hypertrophic differentiation related gene expression in cultured chondrocytes H. Inoue, Y. Arai, R. Terauchi, S. Nakagawa,

Evaluation of TRB-n0224, a Chemically Modified Curcumin for the Treatment of Osteoarthritis R. Nixon, J. Coury, S.S. Shah, N. Chahine, T. Goldstein,

Z. Zhang, W. Liao, Z. Zhang, X. Duan, C. Hou

Replicability of recommended exercise interventions for knee osteoarthritis: a descriptive systematic review of current clinical guidelines and recommendations

Identification of p21 inhibitors to enhance chondrogenesis in osteoarthritic synovial mesenchymal progenitor cells K.L. Bertram, T. Irvine, P. Tailor,

L. Gato-Calvo, Á. Vela-Anero, E. Loures-Fraga, C. Ruiz Romero, F. J

Y. Zhou, L. Resutek, L. Wang, X. Lu Osteoarthritis and Cartilage

M. Cucchiarini, H. Madry, E.F. Terwilliger

Role of TCF4 in signaling crosstalk with NFκB in human chondrocytes

The influence of early osteoarthritic collagen network de-structuring in articular cartilage on the tissue stiffness and swelling properties M. Nickien,

R2−R1ρ as a Potential Biomarker for Tracking Cartilage Matrix Changes in Osteoarthritic Knees after Hyaluronic Acid Injection M. Tanaka, A. Azus, V.

Different responses of healthy, relative healthy and OA chondrocytes with IL1β treatment under hypoxia and normoxia X. Huang, L. Zhong, J. Post, M. Karperien

N. Gómez-Prieto, Á. Vela-Anero, L. Gato-Calvo, C. Ruiz-Romero, R

Y. Levy, A. Hasegawa, S. Patil, M. Lotz, D. D'Lima

Water-soluble C60-(OH)24 fullerene hydroxide as a therapeutic agent against the degeneration of articular cartilage in osteoarthritis N. Yui, H. Yoshioka,

S. Sakata, S. Hayashi, T. Fujishiro, N. Kanzaki, S. Hashimoto, K

M.N. Khan, M.Y. Ansari, T.M. Haqqi Osteoarthritis and Cartilage

Osteoarthritis and Cartilage

Responsiveness of infra-patellar fat pad (IPFP) volume change with severe body weight gain and loss – Data from the OAI E. Steidle-Kloc, T. Dannhauer,

K. Hashimoto, K. El-Hachem, M. Otero, M.B. Goldring

Osteoarthritis and Cartilage

M.L. Roemhildt, A.E. Gauthier Osteoarthritis and Cartilage

Who should have a joint replacement? A plea for more ‘phronesis’

M. F. Pustjens, S. C. Mastbergen, W. H. Noort-Van der Laan, R. J

Emerging role of endothelin receptor type B in regulating chondrogenic and hypertrophic changes of human mesenchymal stem cells M. Au, M. Zhu, W.-J.

N. Khalaj, N.A. Osman, W. Wan Abas, A. Mokhtar

M. Baharuddin, S.-H. Salleh, M. Lee, A. Mohd Noor

Z. Huang, T. Stabler, F. Pei, V. Kraus Osteoarthritis and Cartilage

In vitro release of corticosteroids in a new model of slow release platform in the treatment of osteoarthritis. S. Colen, M. van Rijen, S. Plomp, L.

Osteoarthritis and Cartilage

Increased susceptibility to IL-1 accelerates osteoarthritic change in 3D-cultured chondrocytes and in vivo animal models Y. Takeda, Y. Niki, Y. Fukuhara,

R. L. Trevino, C. A. Pacione, S. Chubinskaya, A. -M. Malfait, M. A

Damps provide a link between joint tissue damage and pain through direct activation of TLR4 expressed by sensory neurons R.E. Miller, P.B. Tran, S. Ishihara,

A peptide temporally enhanced chondrogenesis of mesenchymal stem cells

Evidence for bone mineral density and bone resorption in middle and elderly women with knee osteoarthritis in Shanghai: a cross sectional study Q. Xiaofeng

Walking with increased foot progression angle can reduce joint compression in individuals with knee OA K. Manal, T.S. Buchanan Osteoarthritis and Cartilage

674. Molecular, Biochemical and Biomechanical Analysis of Articular Cartilage Repaired with Genetically Modified Chondrocytes Expressing Insulin-Like.

Monocyte chemoattractant protein 1 induced chondrocytes degeneration and cartilage degradation in osteoarthritis X. yuankun, K. Yan, W. Bin, L. Jian-Hao

Mechanical loading of cartilage explants with joint-specific loading patterns modulates gene expression of lubricin and catabolic matrix enzymes O.R.

Novel juvenile factors for cartilage regeneration

Multivariate pattern analysis of physical activity and cartilage health: data from the osteoarthritis initiative E. Halilaj, T.J. Hastie, G.E. Gold,

Osteoarthritis and Cartilage

R. H. J. Das, M. Sc. , H. Jahr, Ph. D. , J. A. N. Verhaar, M. D. , Ph

Fracture severity predicts OA risk following intra-articular fractures

Imaging biomarker with T1 and T2 mappings in osteoarthritis – In vivo human articular cartilage study C. Yan, C. Wong, T. Li, N. Gong, Q. Chan, K. Chiu

Osteoarthritis year 2012 in review: biology

Osteoarthritis and Cartilage

H. Khan, D. Aitken, C. Ding, L. Blizzard, J. -P. Pelletier, J

J.H. Ylärinne, C. Qu, M.J. Lammi Osteoarthritis and Cartilage

Knee kinematic and kinetic modifications under body weight unloading during overground walking at a constant speed A.G. Fischer, E.M. Debbi, A. Wolf

Adhesive barrier/directional controlled release for cartilage repair by endogenous progenitor cell recruitment G.-I. Im, J.-M. Lee, E.-A. Kim Osteoarthritis.

Amyloid micronetworks for cartilage repair

Hydrogen sulfide donors alleviate IL-1β induced inflammation-like effects in human articular osteoarthritic chondrocytes E.F. Burguera, A. Vela-Anero,

Erratum to “Effect of hyaluronic acid (MW 500–730kDa) on proteoglycan and nitric oxide production in human osteoarthritic chondrocyte cultures exposed.

Effect of hyaluronic acid (MW 500–730kDa) on proteoglycan and nitric oxide production in human osteoarthritic chondrocyte cultures exposed to hydrostatic.

Peroxisome proliferator activated receptor alpha activation decreases inflammatory and destructive responses in osteoarthritic cartilage S. Clockaerts,

Arthritic synovial fluid influences expression of pro- and anti-inflammatory mediators in macrophages S. Lopa, M. Leijs, M. Moretti, E. Lubberts, G.

A. Carlson, B. Bothner, R. June Osteoarthritis and Cartilage

General Information Osteoarthritis and Cartilage

Long-term effects of vitamin d supplementation and maintaining vitamin d sufficiency on knee osteoarthritis over 5 years B. Antony, S. Zheng, J. Burgess,

Presentation transcript:

Osteoarthritis and Cartilage Possible chondroprotective effect of canakinumab: An in vitro study on human osteoarthritic chondrocytes S. Cheleschi, N.A. Pascarelli, O.M. Lucherini, E. Crainz, S. Tenti, M. Galeazzi, G. Collodel, A. Fioravanti, L. Cantarini Osteoarthritis and Cartilage Volume 22, (April 2014) DOI: 10.1016/j.joca.2014.02.276 Copyright © 2014 Terms and Conditions

Figure 1 A) IL-1β levels in the culture medium; B)MMP-1, 3, 13 gene expression. Osteoarthritis and Cartilage 2014 22, DOI: (10.1016/j.joca.2014.02.276) Copyright © 2014 Terms and Conditions