High Frequency of FGFR3 Mutations in Adenoid Seborrheic Keratoses Christian Hafner, Johanna M.M. van Oers, Arndt Hartmann, Michael Landthaler, Robert Stoehr, Hagen Blaszyk, Ferdinand Hofstaedter, Ellen C. Zwarthoff, Thomas Vogt  Journal of Investigative Dermatology  Volume 126, Issue 11, Pages 2404-2407 (November 2006) DOI: 10.1038/sj.jid.5700422 Copyright © 2006 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 1 FGFR3 mutations in adenoid seborrheic keratoses. (a) Hematoxylin and eosin staining of an adenoid SK shows epidermal trabeculae that extend from the epidermis and show branching in the dermis (bar=0.1mm). (b) Multiplex SNaPshot reaction revealed an FGFR3 double mutation in patient no. 15 at codons 248 and 652. (c) Multiplex SNaPshot reaction showed the A393E mutation in patient no. 8, which has not been described in SKs so far. Journal of Investigative Dermatology 2006 126, 2404-2407DOI: (10.1038/sj.jid.5700422) Copyright © 2006 The Society for Investigative Dermatology, Inc Terms and Conditions