Renal Involvement in Multicentric Castleman Disease With Glomeruloid Hemangioma of Skin and Plasmacytoma  Susan Uthup, DM, Krishna Balachandran, MD, Vimala Avadai Ammal, DM, Riyas Abdul Salam, MBBS, Jacob George, DM, Geetha M. Nair, DM, Manju Leela, DM  American Journal of Kidney Diseases  Volume 48, Issue 2, Pages e17-e24 (August 2006) DOI: 10.1053/j.ajkd.2006.04.089 Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

Fig 1 Light micrograph of lymph node biopsy specimen from the axilla (10 μm) shows follicle-like lymphoid structures interspersed with capillaries showing hyalinization, interfollicular vascular proliferation, and sheets of plasma cells. (Hematoxylin and eosin stain.) American Journal of Kidney Diseases 2006 48, e17-e24DOI: (10.1053/j.ajkd.2006.04.089) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

Fig 2 Light micrograph of skin biopsy specimen (20 μm) shows typical glomerulus-like structures within ectatic vascular channels composed of papillary tufts lined by endothelial cells in the dermis: glomeruloid hemangioma. (Hematoxylin and eosin.) American Journal of Kidney Diseases 2006 48, e17-e24DOI: (10.1053/j.ajkd.2006.04.089) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

Fig 3 Light microscopy of glomerulus (10 μm) shows increased mesangial matrix, increased mesangial cellularity, and capillary loop thickening with double contours consistent with MPGN. (Hematoxylin and eosin.) American Journal of Kidney Diseases 2006 48, e17-e24DOI: (10.1053/j.ajkd.2006.04.089) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

Fig 4 Computed tomographic scan of the thorax shows lytic lesion on the second rib. American Journal of Kidney Diseases 2006 48, e17-e24DOI: (10.1053/j.ajkd.2006.04.089) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

Fig 5 Light micrograph of lytic rib lesion (10 μm) shows sheets of plasma cells dispersed in a fibrovascular stroma suggestive of plasmacytoma. (Hematoxylin and eosin.) American Journal of Kidney Diseases 2006 48, e17-e24DOI: (10.1053/j.ajkd.2006.04.089) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions