Afua Adjekum, PhD Student Conceptualizing Trust in Digital Health Systems: A Scoping Review Afua Adjekum1, Alessandro Blasimme1, Effy Vayena1 1Health Ethics and Policy Lab—D-HEST, ETH Zurich 1 Introduction 4 Results and discussion Digital health (DH)1 is driven by the pursuit to improve health systems. Its success however, relies heavily on end-user trust2. Yet, so far, there is scanty evidence on the building blocks of trust in DH. Overall, 278 qualitative, quantitative, mixed methods and intervention studies in English were included. Studies originated from 40 countries and were published between 1998 and 2017. 3 principal stakeholder groups are pertinent to trust: patients, health care professionals and health administrators. Trust elements: enablers (14) and impediments (9). Trust Enablers Altruism Convenience, perceived value and usefulness Customizable design Fair data sharing & access Guidelines for standardized use Improved communication Initial face-to-face contact Interoperability Perceived ease of use Perceived self-efficacy Privacy, security, confidentiality, anonymity Recommendations Sociodemographic factors Stakeholder engagement Trust Impediments Bad quality & inaccurate information Fear of exploitation Inadequate publicity Incompetent vendors & service providers Insufficient training Reduced efficiency & increased workload Socio-demographic factors Unaffordable & inaccessible devices Unreliable technology 2 Objective This study seeks to analyze what relevant stakeholders in DH consider as constitutive elements of trust in DH. 5 Conclusion 3 Method overview Trust in DH technologies and services depends on the interplay of a complex set of enablers and impediments. This study contributes to ongoing efforts to understand what determines trust in DH by different stakeholders to aid in the implementation of innovative DH services. A comprehensive scoping review framework3 of 5 electronic databases (peer-reviewed articles). 6 References United States Food & Drug Administration (2017). "Digital Health." Retrieved January 24 2018, 2018, from https://www.fda.gov/medicaldevices/digitalhealth/. Vayena, E., et al. (2018). "Digital health: meeting the ethical and policy challenges." Swiss Medical Weekly 148(w14571): 1-9. Arksey, H. and L. O'Malley (2005). "Scoping studies: towards a methodological framework." International Journal of Social Research Methodology 8(1): 19-32. 7 Contact Information Afua Adjekum, PhD Student  Phone: +41 44 632 24769 Afua.adjekum@hest.ethz.ch