Volume 148, Issue 5, Pages e4 (May 2015)

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Volume 148, Issue 5, Pages 958-966.e4 (May 2015) Association Between Psychological Distress and Liver Disease Mortality: A Meta- analysis of Individual Study Participants Tom C. Russ, Mika Kivimäki, Joanne R. Morling, John M. Starr, Emmanuel Stamatakis, G. David Batty Gastroenterology Volume 148, Issue 5, Pages 958-966.e4 (May 2015) DOI: 10.1053/j.gastro.2015.02.004 Copyright © 2015 AGA Institute Terms and Conditions

Figure 1 Numbers of study members from induction through to analytic sample and subsequent mortality: individual participant meta-analysis of 16 prospective cohort studies. ALD, alcoholic liver disease. Gastroenterology 2015 148, 958-966.e4DOI: (10.1053/j.gastro.2015.02.004) Copyright © 2015 AGA Institute Terms and Conditions

Figure 2 Multivariable-adjusted HRs (95% CIs) for the association between increasing levels of psychological distress and liver disease mortality: individual participant meta-analysis of 16 prospective cohort studies. Gastroenterology 2015 148, 958-966.e4DOI: (10.1053/j.gastro.2015.02.004) Copyright © 2015 AGA Institute Terms and Conditions

Supplementary Figure 1 Multivariable-adjusted HRs (95% CIs) per SD increase in psychological distress in relation to liver disease mortality according to study: individual participant meta-analysis of 16 prospective cohort studies. I2 = 13.7%. Health Survey for England 1994 is missing because it was excluded from the multivariable models due to missing data. The size of the boxes indicates the relative weights of the studies. Gastroenterology 2015 148, 958-966.e4DOI: (10.1053/j.gastro.2015.02.004) Copyright © 2015 AGA Institute Terms and Conditions

Supplementary Figure 2 Multivariable-adjusted HRs (95% CIs) for the association between increasing levels of psychological distress and (A) alcoholic liver disease mortality and (B) probable nonalcoholic liver disease mortality: individual participant meta-analysis of 16 prospective cohort studies. Gastroenterology 2015 148, 958-966.e4DOI: (10.1053/j.gastro.2015.02.004) Copyright © 2015 AGA Institute Terms and Conditions