Conditional probability density function of age at onset for different current ages (CA) (t). Conditional probability density function of age at onset.

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Copyright ©2001 BMJ Publishing Group Ltd. Emerg Med J 2001;18:
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Presentation transcript:

Conditional probability density function of age at onset for different current ages (CA) (t). Conditional probability density function of age at onset for different current ages (CA) (t). The figures are drawn for SCA2 data with a repeat number of the expanded allele of 37 for an individual at birth (solid), or at a current age of 30 (medium dash), 40 (short dash) or 45 (short dash dot). Based on a log linear parametric model, the estimation of the mean age at onset from birth was 43 years (γG: 3.7428,: 0.2516) (vertical dashed line). As the distribution is log-normal the mode is neither the mean nor the median. SCA, spinocerebellar ataxias. Sophie Tezenas du Montcel et al. J Med Genet doi:10.1136/jmedgenet-2013-102200 ©2014 by BMJ Publishing Group Ltd