Kai Ihnken, MD The Journal of Thoracic and Cardiovascular Surgery

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Presentation transcript:

Hyperoxic cardiopulmonary bypass causes reoxygenation injury and lipid peroxidation Kai Ihnken, MD The Journal of Thoracic and Cardiovascular Surgery Volume 114, Issue 2, Pages 304-305 (August 1997) DOI: 10.1016/S0022-5223(97)70172-7 Copyright © 1997 Mosby, Inc. Terms and Conditions

Fig. 1 Malondialdehyde (MDA) as a measure of lipid peroxidation from systemic venous blood at the start and end of CPB. The hyperoxic group included 10 patients during coronary artery bypass graft operations in which CPB was conducted in a hyperoxic fashion (Po2 = 450 mm Hg). The normoxic group consisted of 10 patients also undergoing coronary artery bypass graft operations in which CPB was run with reduced oxygen levels (Po2 150 mm Hg). The groups did not differ in terms of age, sex, severity of disease, contractility, number of grafts, length of CPB, or ischemic time. *p < 0.05 versus hyperoxic group (analysis of variance). The Journal of Thoracic and Cardiovascular Surgery 1997 114, 304-305DOI: (10.1016/S0022-5223(97)70172-7) Copyright © 1997 Mosby, Inc. Terms and Conditions