Whole-ventricular irradiation for intracranial germ cell tumors: Dosimetric comparison of pencil beam scanned protons, intensity-modulated radiotherapy.

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Presentation transcript:

Whole-ventricular irradiation for intracranial germ cell tumors: Dosimetric comparison of pencil beam scanned protons, intensity-modulated radiotherapy and volumetric- modulated arc therapy Dora Correia, Dario Terribilini, Stefan Zepter, Alessia Pica, Nicola Bizzocchi, Werner Volken, Sonja Stieb, Frank Ahlhelm, Evelyn Herrmann, Michael K. Fix, Peter Manser, Daniel M. Aebersold, Damien C. Weber Clinical and Translational Radiation Oncology Volume 15, Pages 53-61 (February 2019) DOI: 10.1016/j.ctro.2019.01.002 Copyright © 2019 The Authors Terms and Conditions

Fig. 1 Comparison of dose distribution in three different modalities for a patient with intracranial germ cell tumor: (A) Pencil beam scanning proton beam therapy (PBS-PT) plan. (B) Intensity-modulated radiotherapy (IMRT) plan. (C) Volumetric modulated arc therapy (VMAT) plan. PTV_Low is delineated in orange, PTV_High in red. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.) Clinical and Translational Radiation Oncology 2019 15, 53-61DOI: (10.1016/j.ctro.2019.01.002) Copyright © 2019 The Authors Terms and Conditions

Fig. 2 Cumulative dose-volume histograms (DVH) (mean dose, n = 11) with range for PTV coverage with PBS-PT, IMRT and VMAT plans. Clinical and Translational Radiation Oncology 2019 15, 53-61DOI: (10.1016/j.ctro.2019.01.002) Copyright © 2019 The Authors Terms and Conditions

Fig. 3 Cumulative DVH (mean dose, n = 11) with range for (N)OAR with a significant dose difference for PBS-PT compared to photons. Clinical and Translational Radiation Oncology 2019 15, 53-61DOI: (10.1016/j.ctro.2019.01.002) Copyright © 2019 The Authors Terms and Conditions