Clinical Outcomes With the Epicholorohydrin-Modified Porcine Aortic Heart Valve: A 15- Year Follow-Up Xufeng Wei, MD, PhD, Wei Yi, MD, PhD, Wensheng Chen,

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Clinical Outcomes With the Epicholorohydrin-Modified Porcine Aortic Heart Valve: A 15- Year Follow-Up Xufeng Wei, MD, PhD, Wei Yi, MD, PhD, Wensheng Chen, MD, PhD, Xinliang Ma, MD, PhD, Wayne Bond Lau, MD, Hongbing Wang, MD, Dinghua Yi, MD, PhD The Annals of Thoracic Surgery Volume 89, Issue 5, Pages 1417-1424 (May 2010) DOI: 10.1016/j.athoracsur.2010.02.009 Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 The epichlorohydrin-modified porcine aortic heart valve. (A) The BioRens Porcine Valve made by BalMedic (Beijing, China). (B) The flexible cobalt–nickel alloy wire stent and covered with a Dacron sewing ring. (C, D) The outlet and inlet of the BioRens Porcine Valve. The Annals of Thoracic Surgery 2010 89, 1417-1424DOI: (10.1016/j.athoracsur.2010.02.009) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Actuarial (Kaplan-Meier) survival curves. (AVR = aortic valve replacement; DVR = double-valve replacement; MVR = mitral valve replacement; TVR = tricuspid valve replacement.) The Annals of Thoracic Surgery 2010 89, 1417-1424DOI: (10.1016/j.athoracsur.2010.02.009) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Actuarial freedom from valve-related death. (AVR = aortic valve replacement; DVR = double-valve replacement; MVR = mitral valve replacement; TVR = tricuspid valve replacement.) The Annals of Thoracic Surgery 2010 89, 1417-1424DOI: (10.1016/j.athoracsur.2010.02.009) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Actuarial freedom from structural valve disease (SVD). (AVR = aortic valve replacement; DVR = double-valve replacement; MVR = mitral valve replacement; TVR = tricuspid valve replacement.) The Annals of Thoracic Surgery 2010 89, 1417-1424DOI: (10.1016/j.athoracsur.2010.02.009) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

Fig 5 Freedom from reoperations. (AVR = aortic valve replacement; DVR = double-valve replacement; MVR = mitral valve replacement; TVR = tricuspid valve replacement.) The Annals of Thoracic Surgery 2010 89, 1417-1424DOI: (10.1016/j.athoracsur.2010.02.009) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

Fig 6 Actuarial freedom from thromboembolism (TE). (AVR = aortic valve replacement; DVR = double-valve replacement; MVR = mitral valve replacement; TVR = tricuspid valve replacement.) The Annals of Thoracic Surgery 2010 89, 1417-1424DOI: (10.1016/j.athoracsur.2010.02.009) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

Fig 7 Actuarial freedom from bleed event. (AVR = aortic valve replacement; DVR = double-valve replacement; MVR = mitral valve replacement; TVR = tricuspid valve replacement.) The Annals of Thoracic Surgery 2010 89, 1417-1424DOI: (10.1016/j.athoracsur.2010.02.009) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

Fig 8 Actuarial freedom from operated valve endocarditis (OVE). (AVR = aortic valve replacement; DVR = double-valve replacement; MVR = mitral valve replacement; TVR = tricuspid valve replacement.) The Annals of Thoracic Surgery 2010 89, 1417-1424DOI: (10.1016/j.athoracsur.2010.02.009) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions