A Randomized Phase II Study of Gemcitabine and Carboplatin with or without Cediranib as First-Line Therapy in Advanced Non–Small-Cell Lung Cancer: North.

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A Randomized Phase II Study of Gemcitabine and Carboplatin with or without Cediranib as First-Line Therapy in Advanced Non–Small-Cell Lung Cancer: North Central Cancer Treatment Group Study N0528 Grace K. Dy, MD, Sumithra J. Mandrekar, PhD, Garth D. Nelson, MS, Jeffrey P. Meyers, BA, Araba A. Adjei, PhD, Helen J. Ross, MD, Rafat H. Ansari, MD, Alan P. Lyss, MD, Philip J. Stella, MD, Steven E. Schild, MD, Julian R. Molina, MD, PhD, Alex A. Adjei, MD, PhD Journal of Thoracic Oncology Volume 8, Issue 1, Pages 79-88 (January 2013) DOI: 10.1097/JTO.0b013e318274a85d Copyright © 2012 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 1 CONSORT trial flow diagram. Journal of Thoracic Oncology 2013 8, 79-88DOI: (10.1097/JTO.0b013e318274a85d) Copyright © 2012 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 2 Kaplan–Meier curves in overall population for (A) progression-free survival and (B),overall survival. Journal of Thoracic Oncology 2013 8, 79-88DOI: (10.1097/JTO.0b013e318274a85d) Copyright © 2012 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 3 Kaplan–Meier curves for overall survival according to polymorphic variants A, FGFR1 rs7012413, (B) FGFR2 rs2912791, and (C) VEGFR3 rs11748431. Journal of Thoracic Oncology 2013 8, 79-88DOI: (10.1097/JTO.0b013e318274a85d) Copyright © 2012 International Association for the Study of Lung Cancer Terms and Conditions